Accelerated visualization of selected intracranial arteries by cycled super-selective arterial spin labeling

Accelerated visualization of selected intracranial arteries by cycled super-selective arterial spin labeling
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通过循环超选择性动脉自旋标记加速选定颅内动脉的可视化

DOI:
10.1007/s10334-016-0574-z
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发表时间:
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期刊:
Magnetic Resonance Materials in Physics, Biology and Medicine
影响因子:
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通讯作者:
Helle M
Helle M
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文献类型:
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作者:
Lindner T;Larsen N;Jansen O;Helle M

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目的加速超选择性动脉自旋标记(ASL)血管造影术通过使用一个单一的控制条件表示为cycled super-selective arterial spin labeling.Materials和methodsA单一的非选择性控制图像是由选择性标记图像共享的采集。在测量过程中,通过几何方式将标记焦点的位置改变到多个感兴趣动脉,可以实现动脉选择性成像。所提出的方法相比,传统的超选择性成像的标记效率的内部和外部的标记焦点,使用数值模拟和体内测量。此外,信号噪声比的图像进行比较,非选择性ASL血管造影和分析,使用双向ANOVA检验和计算Pearson的相关系数。ResultsThe结果表明,标记效率不降低标记的动脉内,但可以增加作为一个函数的距离感兴趣的动脉相比,传统的超选择性ASL。在最终的图像中,可以观察到图像质量没有统计学上的显著差异,而采集时间可以减少时,主要脑供血动脉被tagged.ConclusionUsing超选择性动脉自旋标记,一个单一的非选择性控制采集足以重建脑血管的选择性血管造影,从而加速颅内主要动脉的图像采集而没有显著的信息损失。
ObjectiveTo accelerate super-selective arterial spin labeling (ASL) angiography by using a single control condition denoted as cycled super-selective arterial spin labeling.Materials and methodsA single non-selective control image is acquired that is shared by selective label images. Artery-selective imaging is possible by geometrically changing the position of the labeling focus to more than one artery of interest during measurement. The presented approach is compared to conventional super-selective imaging in terms of its labeling efficiency inside and outside the labeling focus using numerical simulations and in vivo measurements. Additionally, the signal-to-noise ratios of the images are compared to non-selective ASL angiography and analyzed using a two-way ANOVA test and calculating the Pearson’s correlation coefficients.ResultsThe results indicate that the labeling efficiency is not reduced within the labeled artery, but can increase as a function of distance to the artery of interest when compared to conventional super-selective ASL. In the final images, no statistically significant difference of image quality can be observed while the acquisition duration could be reduced when the major brain feeding arteries are being tagged.ConclusionUsing super-selective arterial spin labeling, a single non-selective control acquisition suffices for reconstructing selective angiograms of the cerebral vasculature, thereby accelerating image acquisition of the major intracranial arteries without notable loss of information.
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