An ultrasensitive micropillar-enabled acoustic wave (μPAW) microdevice for real-time viscosity measurement
An ultrasensitive micropillar-enabled acoustic wave (μPAW) microdevice for real-time viscosity measurement
复制标题
用于实时粘度测量的超灵敏微柱声波 (μPAW) 微型设备
DOI：
10.1007/s00542-023-05530-w
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Sun, Hongwei
中科院分区：
文献类型：
--
作者：
Esfahani, Ilia Chiniforooshan;Ji, Siqi;Alamgir Tehrani, Nastaran;Sun, Hongwei
粘度测量由于其在制药、食品工业、化妆品工业和生物医学诊断等领域的广泛应用，最近引起了相当大的关注。石英晶体微天平 (QCM) 等声波传感器是众所周知的质量传感器，也显示出其测量液体粘度的能力。然而，基于 QCM 的粘度测量装置面临的挑战在于灵敏度低和响应不稳定。在此，我们报告了一种超灵敏的微柱声波（μPAW）粘度计，通过在QCM基板上制造明确的聚甲基丙烯酸甲酯（PMMA）微柱，由于微柱和QCM基板之间独特的振动耦合，可以实现液体粘度的超高灵敏度和稳定的响应。基于 μPAW 的粘度计的测量灵敏度比传统 QCM 粘度计提高了 20 倍，在测量低至 0.054 wt% 的蔗糖液体粘度时实现了出色的检测限 (LOD)。这项工作中开发的微型装置是一种很有前途的液体粘度测量工具。
Viscosity measurement has recently captured considerable attention due to its wide range of applications in fields such as pharmacy, food industry, cosmetic industry, and biomedical diagnostics. Acoustic wave sensors such as quartz crystal microbalance (QCM) are well-known mass sensors that also show their capability in measuring liquid viscosity. However, the challenges for QCM-based viscosity measurement devices lie in their low sensitivity and unstable response. Herein, we report an ultrasensitive micropillar-enabled acoustic wave (μPAW) viscometer by fabricating well-defined polymethyl methacrylate (PMMA) micropillars on a QCM substrate to achieve ultrahigh sensitivity for liquid viscosity with a stable response thanks to a unique vibration coupling between the micropillar and QCM substrate. The μPAW based viscometer shows a 20-fold improvement in the measurement sensitivity over traditional QCM viscometers and achieved an excellent limit of detection (LOD) while measuring the viscosity of sucrose liquid as low as 0.054 wt%. The microdevice developed in this work is a promising tool for the viscosity measurement of liquids.
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DOI：
10.1111/j.1467-2494.1992.tb00045.x
发表时间：
1992-01-01
影响因子：
2.3
作者：
TADROS T F
通讯作者：
TADROS T F
影响因子：
4.3
作者：
Esmaeilzadeh, Hamed;Su, Junwei;Sun, Hongwei
通讯作者：
Sun, Hongwei
液体粘度测定
DOI：
10.1007/978-3-319-04858-1
发表时间：
2014
期刊：
Sensors and Actuators A: Physical
影响因子：
--
作者：
S. V. Gupta
通讯作者：
S. V. Gupta
影响因子：
15.3
作者：
Cullen, PJ;Duffy, AP;O'Callaghan, DJ
通讯作者：
O'Callaghan, DJ
使用复杂几何形状的旋转流变测量——综述
影响因子：
3.2
作者：
P. Cullen;C. O’Donnell;M. Houška
通讯作者：
M. Houška