Seroprevalence dynamics of European bat lyssavirus type 1 in a multispecies bat colony.

Seroprevalence dynamics of European bat lyssavirus type 1 in a multispecies bat colony.
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DOI:
10.3390/v6093386
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发表时间:
2014-09-04
期刊:
Viruses
影响因子:
--
通讯作者:
Serra-Cobo J
Serra-Cobo J
中科院分区:
其他
文献类型:
--
作者:
López-Roig M;Bourhy H;Lavenir R;Serra-Cobo J

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我们报告了一个积极的监测研究发生的特异性抗体欧洲蝙蝠Lysavirus 1型(EBLV-1)的蝙蝠物种,迄今为止几乎没有研究,共享同一避难所。从2004年到2012年,从9个蝙蝠物种中获得了406份血清。对血样进行改良的荧光抗体病毒中和试验,以测定抗体滴度。在所分析的9个物种中的6个物种中检测到EBLV-1-中和抗体(伏翼、库利伏翼、沙氏Hypsugo savii、奥地利腹蛛、埃及Eptesicus teniotis和Tadarida teniotis)。在所调查的蝙蝠中,雌蝙蝠的血清阳性率(20.21%,95%CI:14.78%~ 26.57%)与雄蝙蝠的血清阳性率(15.02%,95%CI:10.51%~ 20.54%)无显著性差异。结果表明,中华绒螯蟹血清学阳性蝙蝠数的年际变化规律与中华绒螯蟹血清学阳性蝙蝠数的年际变化规律一致。teniotis和P. austriacus在2007年显示出高峰(EBLV-1流行率的>70%)。然而,在T. teniotis和P. austriacus。这些物种的行为生态学可以解释EBLV-1血清阳性率的不同年度波动。
We report an active surveillance study of the occurrence of specific antibodies to European Bat Lyssavirus Type 1 (EBLV-1) in bat species, scarcely studied hitherto, that share the same refuge. From 2004 to 2012, 406 sera were obtained from nine bat species. Blood samples were subjected to a modified fluorescent antibody virus neutralization test to determine the antibody titer. EBLV-1-neutralizing antibodies were detected in six of the nine species analyzed (Pipistrellus pipistrellus, P. kuhlii, Hypsugo savii, Plecotus austriacus, Eptesicus serotinus and Tadarida teniotis). Among all bats sampled, female seroprevalence (20.21%, 95% CI: 14.78%–26.57%) was not significantly higher than the seroprevalence in males (15.02%, 95% CI: 10.51%–20.54%). The results showed that the inter-annual variation in the number of seropositive bats in T. teniotis and P. austriacus showed a peak in 2007 (>70% of EBLV-1 prevalence). However, significant differences were observed in the temporal patterns of the seroprevalence modeling of T. teniotis and P. austriacus. The behavioral ecology of these species involved could explain the different annual fluctuations in EBLV-1 seroprevalence.
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