Short-Term Effects of Heat on Mortality and Effect Modification by Air Pollution in 25 Italian Cities.

Short-Term Effects of Heat on Mortality and Effect Modification by Air Pollution in 25 Italian Cities.
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DOI:
10.3390/ijerph15081771
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发表时间:
2018-08-17
影响因子:
--
通讯作者:
Stafoggia M
Stafoggia M
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Scortichini M;De Sario M;de'Donato FK;Davoli M;Michelozzi P;Stafoggia M

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关于极端温度和空气污染对健康影响的证据非常丰富。然而,很少有研究关注它们之间的相互作用。本研究的目的是评估25个意大利城市的每日PM10和臭氧作为温度与自然死亡率之间关系的潜在影响调节剂。对每个城市进行了时间序列分析。为了评估相互作用,定义了平均气温(滞后0-3)与PM10或臭氧(滞后0-5)之间的张量积,并推断了低、中、高水平污染物的温度估计值。热效应是用温度升高75到99个百分位数时死亡率变化的百分比来估计的。结果按地理区域汇总。发现了空气污染物造成的温差-死亡率风险。对于PM10,北方的估计范围从3.9%(低PM10)到14.1%(高PM10),中部从3.6%到24.4%,南部从7.5%到21.6%。在意大利北部和中部,臭氧同样改变了与温度相关的死亡率,而在南部没有观察到任何改变。这项研究强调了热和空气污染对死亡率的协同效应。考虑到预计意大利等地中海国家的热浪和停滞事件将会增加,是时候将空气污染纳入公共卫生防热计划了。
Evidence on the health effects of extreme temperatures and air pollution is copious. However few studies focused on their interaction. The aim of this study is to evaluate daily PM10 and ozone as potential effect modifiers of the relationship between temperature and natural mortality in 25 Italian cities. Time-series analysis was run for each city. To evaluate interaction, a tensor product between mean air temperature (lag 0–3) and either PM10 or ozone (both lag 0–5) was defined and temperature estimates were extrapolated at low, medium, and high levels of pollutants. Heat effects were estimated as percent change in mortality for increases in temperature between 75th and 99th percentiles. Results were pooled by geographical area. Differential temperature-mortality risks by air pollutants were found. For PM10, estimates ranged from 3.9% (low PM10) to 14.1% (high PM10) in the North, from 3.6% to 24.4% in the Center, and from 7.5% to 21.6% in the South. Temperature-related mortality was similarly modified by ozone in northern and central Italy, while no effect modification was observed in the South. This study underlines the synergistic effects of heat and air pollution on mortality. Considering the predicted increase in heat waves and stagnation events in the Mediterranean countries such as Italy, it is time to enclose air pollution within public health heat prevention plans.
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