Interpersonal Stress Severity Longitudinally Predicts Adolescent Girls' Depressive Symptoms: the Moderating Role of Subjective and HPA Axis Stress Responses.
Interpersonal Stress Severity Longitudinally Predicts Adolescent Girls' Depressive Symptoms: the Moderating Role of Subjective and HPA Axis Stress Responses.
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DOI：
10.1007/s10802-018-0483-x
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发表时间：
2019-05
影响因子：
3.6
通讯作者：
Prinstein MJ
中科院分区：
文献类型：
--
作者：
Owens SA;Helms SW;Rudolph KD;Hastings PD;Nock MK;Prinstein MJ
近几十年来，青少年抑郁症的压力反应模型引起了人们的关注，但仍不清楚为什么只有某些青少年容易受到压力的抑郁影响，而其他青少年则不然。基于证据表明，对压力的情感和生理反应会减轻压力暴露对抑郁症的影响，当前的研究检验了人际压力的严重程度、主观情感反应性和下丘脑-垂体-肾上腺（HPA）轴对急性体内心理社会压力源的反应性之间的相互作用是否能够前瞻性地预测九个月后的抑郁症状。对由 182 名青春期女孩（12-16 岁）组成的临床超采样组进行了检验，以确保检查尽可能广泛的风险。在体内压力任务之前和之后收集情感和唾液皮质醇样本的自我报告测量，以分别评估情感反应性和 HPA 轴反应性。使用半结构化访谈评估基线和九个月之间的人际压力严重程度，并根据严重程度和内容主题（即人际与非人际）进行客观编码。结果表明，只有对压力的情感反应较高的青春期女孩，经历过严重的人际压力才能纵向预测抑郁症状的水平升高，并且表明，对于压力生理反应较高的女孩来说，压力的这些有害影响最为严重。研究结果表明，在评估青少年抑郁风险时，检查情感和生理压力反应可能至关重要。
In recent decades, stress response models of adolescent depression have gained attention, but it remains unclear why only certain adolescents are vulnerable to the depressogenic effects of stress while others are not. Building on evidence that affective and physiological responses to stress moderate the impact of stress exposure on depression, the current study examined whether the interaction between severity of interpersonal stress, subjective affective reactivity, and hypothalamic-pituitary-adrenal (HPA) axis reactivity to an acute, in-vivo psychosocial stressor prospectively predicted depressive symptoms nine months later. Hypotheses were examined with a clinically-oversampled group of 182 adolescent girls (aged 12–16) to ensure an examination of the widest possible range of risk. Self-report measures of affect and salivary cortisol samples were collected before and after an in-vivo stress task to assess affective reactivity and HPA axis reactivity, respectively. Severity of interpersonal stress between baseline and nine months was assessed using a semi-structured interview and was objectively coded for severity and content theme (i.e., interpersonal vs. non-interpersonal). Results indicate that experiences of severe interpersonally-themed stress predict elevated levels of depressive symptoms longitudinally only for adolescent girls with elevated affective reactivity to stress, and suggest that these deleterious effects of stress are most exacerbated for girls with elevated physiological responses to stress. Findings suggest that it may be critical to examine both affective and physiological stress responses when assessing risk for depression in adolescents.
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影响因子：
3.6
作者：
Laurent, J;Catanzaro, SJ;Gathright, T
通讯作者：
Gathright, T
影响因子：
4.2
作者：
Gruber, June;Kogan, Aleksandr;Mauss, Iris B.
通讯作者：
Mauss, Iris B.
影响因子：
3.2
作者：
KIRSCHBAUM, C;PIRKE, KM;HELLHAMMER, DH
通讯作者：
HELLHAMMER, DH
影响因子：
3.7
作者：
Adam, Emma K.;Doane, Leah D.;Zinbarg, Richard E.;Mineka, Susan;Craske, Michelle G.;Griffith, James W.
通讯作者：
Griffith, James W.
皮质醇对实验操纵的年轻人的心理压力的反应性，抑郁症风险各不相同。
影响因子：
7.4
作者：
Morris, Matthew C.;Rao, Uma;Wang, Lily;Garber, Judy
通讯作者：
Garber, Judy