Association between dietary inflammatory index and inflammatory markers in the HELENA study.
Association between dietary inflammatory index and inflammatory markers in the HELENA study.
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DOI：
10.1002/mnfr.201600707
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发表时间：
2017-06
影响因子：
5.2
通讯作者：
Huybrechts I
中科院分区：
文献类型：
--
作者：
Shivappa N;Hebert JR;Marcos A;Diaz LE;Gomez S;Nova E;Michels N;Arouca A;González-Gil E;Frederic G;González-Gross M;Castillo MJ;Manios Y;Kersting M;Gunter MJ;De Henauw S;Antonios K;Widhalm K;Molnar D;Moreno L;Huybrechts I
先前的研究表明，饮食与成年人的低度全身炎症有关。然而，目前还没有研究探讨饮食潜在炎症与饮食行为可能与成人不同的青少年的低度全身炎症之间的关联。我们在 HELENA 横断面研究中检查了 24 小时回忆衍生饮食炎症指数 (DII) 评分对 532 名欧洲青少年炎症的预测能力。 DII 是源自文献的饮食指数，旨在预测炎症。 DII 按每 1000 卡路里计算，并针对 C 反应蛋白 (CRP)、白细胞介素 (IL)-1、2、4、10、TNF-α、ICAM、VCAM 和 IFN-γ 进行测试。所有炎症标记物均具有非正态分布，因此进行了对数转换。使用多变量线性回归进行分析，调整年龄、性别、城市、体重指数、吸烟和体力活动。促炎饮食（较高的 DII 评分）与各种炎症标志物水平升高相关：TNF-α、IL-1、2、IFN-γ 和 VCAM（bDIIt3vs1= 0.13，95% CI：0.001，0.25；0.13，95% CI 0.001，0.25；0.40，95% CI：0.03， 0.77；0.53，95% CI：0.05，1.01；0.07，95% CI：0.01，0.13）。这些结果强化了这样一个事实：饮食作为一个整体，在改变青少年炎症方面发挥着重要作用。先前的研究表明，饮食与成年人的低度全身炎症有关。然而，目前还没有研究探讨饮食潜在炎症与饮食行为可能与成人不同的青少年的低度全身炎症之间的关联。在欧洲青少年营养 (HELENA) 横断面研究的健康生活方式中，较高的 DII 分数证明促炎饮食与各种炎症标志物水平升高相关。
Previous research has shown that diet is associated with low-grade systemic inflammation among adults. However, no study has yet been conducted to explore the association between inflammatory potential of diet and low-grade systemic inflammation among adolescents whose dietary behavior may be different from adults. We examine the predictive ability of 24-hour recall-derived dietary inflammatory index (DII) scores on inflammation among 532 European adolescents in the HELENA cross-sectional study. The DII is a literature-derived dietary index developed to predict inflammation. The DII was calculated per 1000 calories and was tested against C-reactive protein (CRP), interleukins (IL)-1,2,4, 10, TNF-α, ICAM, VCAM and IFN-γ. All inflammatory markers had non-normal distributions and therefore were log transformed. Analyses were performed using multivariable linear regression, adjusting for age, sex, city, BMI, smoking and physical activity. Pro-inflammatory diet (higher DII scores) was associated with increased levels of various inflammatory markers: TNF-α, IL-1, 2, IFN-γ and VCAM (bDIIt3vs1= 0.13, 95% CI: 0.001, 0.25; 0.13, 95% CI 0.001, 0.25; 0.40, 95% CI: 0.03, 0.77; 0.53, 95% CI: 0.05, 1.01; 0.07, 95% CI: 0.01, 0.13 respectively). These results reinforce the fact that diet, as a whole, plays an important role in modifying inflammation in adolescents. Previous research has shown that diet is associated with low-grade systemic inflammation among adults. However, no study has yet been conducted to explore the association between inflammatory potential of diet and low-grade systemic inflammation among adolescents whose dietary behavior may be different from adults. A pro-inflammatory diet as evidenced by higher DII scores is associated with increased levels of various inflammatory markers in the HEalthy Lifestyle in Europe by Nutrition in Adolescents (HELENA) cross-sectional study.
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影响因子：
5.8
作者：
Ferrucci, L;Cherubini, A;Guralnik, JM
通讯作者：
Guralnik, JM
影响因子：
5
作者：
Julian-Almarcegui, Cristina;Bel-Serrat, Silvia;Huybrechts, Inge
通讯作者：
Huybrechts, Inge
影响因子：
13.6
作者：
Dehne, LI;Klemm, C;Hermann-Kunz, E
通讯作者：
Hermann-Kunz, E
影响因子：
7.1
作者：
Houston, Denise K.;Nicklas, Barbara J.;Kritchevsky, Stephen B.
通讯作者：
Kritchevsky, Stephen B.
DOI：
10.1186/0778-7367-70-14
发表时间：
2012-06-19
期刊：
Archives of public health = Archives belges de sante publique
影响因子：
--
作者：
Béghin L;Huybrechts I;Vicente-Rodríguez G;De Henauw S;Gottrand F;Gonzales-Gross M;Dallongeville J;Sjöström M;Leclercq C;Dietrich S;Castillo M;Plada M;Molnar D;Kersting M;Gilbert CC;Moreno LA
通讯作者：
Moreno LA