Mapping of quantitative trait loci for flesh colour and growth traits in Atlantic salmon (Salmo salar).
Mapping of quantitative trait loci for flesh colour and growth traits in Atlantic salmon (Salmo salar).
复制标题
DOI：
10.1186/1297-9686-42-17
复制
发表时间：
2010-06-04
期刊：
影响因子：
--
通讯作者：
Våge DI
中科院分区：
文献类型：
--
作者：
Baranski M;Moen T;Våge DI
鲑科鱼类的肉色和生长相关性状在商业上都很重要，从生理和进化的角度来看也很有意义。本研究的目的是确定数量性状位点（QTL）影响肉色和生长相关性状的F2人口来自一个孤立的，内陆野生人口在挪威（Byglands Bleke）和商业生产人口。分布在大西洋鲑鱼的所有29个连锁群的128个信息微卫星位点在4个F2家族的个体中进行了基因分型，这些家族是从肉色分布的末端选择的。23个额外的位点和两个额外的家庭进行基因分型的连锁群窝藏假定的QTL。QTL分析使用线交叉模型假设固定的替代QTL等位基因和半同胞模型，没有假设的数量和频率的QTL等位基因在创始人人口。一个中度到较强的表型相关之间的颜色，长度和重量性状。共检测到13个全基因组显著性QTL，其中3个为全基因组显著性QTL（Chr 6、Chr 26和Chr 4）。此外，共检测到32个QTL（全染色体P < 0.05）。利用半同胞模型，共检测到6个全基因组显著QTL，其中2个为肉色QTL（Chr 26和Chr 4），41个为提示QTL（全染色体P < 0.05）。基于半同胞分析，这两个全基因组显著的QTL解释了24%的表型变异。在大西洋鲑鱼F2群体中发现了大量与肉质和生长性状相关的显着且提示性的QTL。Chr 26和Chr 4为影响肉色的显著QTL提供了最强的证据，而Chr 10，Chr 5和Chr 4为影响生长性状（长度和重量）的显著QTL提供了最强的证据。这些QTL可能是用于标记辅助选择的强有力的候选者，并为进一步表征肉色和生长的遗传成分提供了起点。
Flesh colour and growth related traits in salmonids are both commercially important and of great interest from a physiological and evolutionary perspective. The aim of this study was to identify quantitative trait loci (QTL) affecting flesh colour and growth related traits in an F2 population derived from an isolated, landlocked wild population in Norway (Byglands Bleke) and a commercial production population. One hundred and twenty-eight informative microsatellite loci distributed across all 29 linkage groups in Atlantic salmon were genotyped in individuals from four F2 families that were selected from the ends of the flesh colour distribution. Genotyping of 23 additional loci and two additional families was performed on a number of linkage groups harbouring putative QTL. QTL analysis was performed using a line-cross model assuming fixation of alternate QTL alleles and a half-sib model with no assumptions about the number and frequency of QTL alleles in the founder populations. A moderate to strong phenotypic correlation was found between colour, length and weight traits. In total, 13 genome-wide significant QTL were detected for all traits using the line-cross model, including three genome-wide significant QTL for flesh colour (Chr 6, Chr 26 and Chr 4). In addition, 32 suggestive QTL were detected (chromosome-wide P < 0.05). Using the half-sib model, six genome-wide significant QTL were detected for all traits, including two for flesh colour (Chr 26 and Chr 4) and 41 suggestive QTL were detected (chromosome-wide P < 0.05). Based on the half-sib analysis, these two genome-wide significant QTL for flesh colour explained 24% of the phenotypic variance for this trait. A large number of significant and suggestive QTL for flesh colour and growth traits were found in an F2 population of Atlantic salmon. Chr 26 and Chr 4 presented the strongest evidence for significant QTL affecting flesh colour, while Chr 10, Chr 5, and Chr 4 presented the strongest evidence for significant QTL affecting growth traits (length and weight). These QTL could be strong candidates for use in marker-assisted selection and provide a starting point for further characterisation of the genetic components underlying flesh colour and growth.
登录
查看更多内容
影响因子：
2.4
作者：
Nones, K;Ledur, MC;Coutinho, LL
通讯作者：
Coutinho, LL
影响因子：
1.7
作者：
Artieri, CG;Mitchell, LA;Davidson, WS
通讯作者：
Davidson, WS
影响因子：
4.5
作者：
IWAMOTO, RN;MYERS, JM;HERSHBERGER, WK
通讯作者：
HERSHBERGER, WK
影响因子：
2.9
作者：
Phillips RB;Keatley KA;Morasch MR;Ventura AB;Lubieniecki KP;Koop BF;Danzmann RG;Davidson WS
通讯作者：
Davidson WS
影响因子：
4.5
作者：
Quinton, CD;McMillan, I;Glebe, BD
通讯作者：
Glebe, BD