Multi-voxel pattern analysis of selective representation of visual working memory in ventral temporal and occipital regions.
Multi-voxel pattern analysis of selective representation of visual working memory in ventral temporal and occipital regions.
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DOI：
10.1016/j.neuroimage.2013.01.055
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发表时间：
2013-06
期刊：
影响因子：
5.7
通讯作者：
Leung, Hoi-Chung
中科院分区：
文献类型：
--
作者：
Han, Xufeng;Berg, Alexander C.;Oh, Hwamee;Samaras, Dimitris;Leung, Hoi-Chung
关键词：
以前的单变量分析结果表明，海马旁回（PHG），而不是梭状回（FG）的活动水平反映了选择性维护的线索图片类别，目前的结果从多体素模式分析（MVPA）表明，这两个区域的空间反应模式可以用来区分所选择的图片类别在工作记忆中。腹侧颞叶和枕叶区包括PHG和FG被证明是专门用于感知和处理不同类型的视觉信息，但它们在视觉工作记忆表征中的作用尚不清楚。为了测试PHG和FG是否显示空间反应模式，反映选择性维护的任务相关的视觉工作记忆相比，其他后关联区域，我们重新分析了数据从以前的功能磁共振成像研究的视觉工作记忆与线索插入延迟识别任务的延迟期间。FG和PHG激活模式的分类为选定的类别（脸或场景）在线索阶段是远远高于机会使用分类器训练的fMRI数据从线索或探测阶段。在其他颞叶和枕叶区域的线索图片类别在线索阶段的活动分类是相对不太一致的，即使他们的活动分类在探头识别相媲美的FG和PHG。总之，这些研究结果表明，FG和PHG进行相关的线索视觉类别的信息，和他们的空间激活模式在选择性维护过程中似乎匹配那些在视觉识别。
While previous results from univariate analysis showed that the activity level of the parahippocampal gyrus (PHG) but not the fusiform gyrus (FG) reflects selective maintenance of the cued picture category, present results from multi-voxel pattern analysis (MVPA) showed that the spatial response patterns of both regions can be used to differentiate the selected picture category in working memory. The ventral temporal and occipital areas including the PHG and FG have been shown to be specialized in perceiving and processing different kinds of visual information, though their role in the representation of visual working memory remains unclear. To test whether the PHG and FG show spatial response patterns that reflect selective maintenance of task-relevant visual working memory in comparison to other posterior association regions, we reanalyzed data from a previous fMRI study of visual working memory with a cue inserted during the delay period of a delayed recognition task. Classification of FG and PHG activation patterns for the selected category (face or scene) during the cue phase was well above chance using classifiers trained with fMRI data from the cue or probe phase. Classification of activity in other temporal and occipital regions for the cued picture category during the cue phase was relatively less consistent even though classification of their activity during the probe recognition was comparable to the FG and PHG. In sum, these findings suggest that the FG and PHG carry information relevant to the cued visual category, and their spatial activation patterns during selective maintenance seem to match those during visual recognition.
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DOI：
10.1523/jneurosci.4667-10.2011
发表时间：
2011-01-26
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Morgan LK;Macevoy SP;Aguirre GK;Epstein RA
通讯作者：
Epstein RA
影响因子：
64.8
作者：
Epstein, R;Kanwisher, N
通讯作者：
Kanwisher, N
影响因子：
4.8
作者：
Fox, Christopher J.;Iaria, Giuseppe;Barton, Jason J. S.
通讯作者：
Barton, Jason J. S.
影响因子：
3.6
作者：
Postle, BR;Druzgal, TJ;D'Esposito, M
通讯作者：
D'Esposito, M
影响因子：
56.9
作者：
Polyn, SM;Natu, VS;Norman, KA
通讯作者：
Norman, KA