Corneal Densitometry After Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser-Assisted LASIK (FS-LASIK): 5-Year Prospective Comparative Study.
Corneal Densitometry After Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser-Assisted LASIK (FS-LASIK): 5-Year Prospective Comparative Study.
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小切口晶状体摘除术 (SMILE) 和飞秒激光辅助 LASIK (FS-LASIK) 后的角膜密度测量：5 年前瞻性比较研究
DOI：
10.3389/fmed.2020.521078
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发表时间：
2020
影响因子：
3.9
通讯作者：
Zhou X
中科院分区：
文献类型：
--
作者：
Wei R;Li M;Yang W;Shen Y;Zhao Y;Fu D;Shang J;Zhang J;Choi J;Zhou X
目的：研究近视或近视散光患者小切口角膜基质透镜摘除术 (SMILE) 与飞秒激光辅助 LASIK (FS-LASIK) 术后角膜密度 (CD) 的长期变化。方法：对接受 SMILE 的 38 名患者（13 名男性）的 66 只眼和接受 FS-LASIK 的 29 名患者（5 名男性）的 54 只眼进行前瞻性分析。所有患者均在术前、术后 6-12 个月和 5 年进行眼部检查。使用 Pentacam Scheimpflug 成像系统在角膜前 120 μm、角膜中和后 60 μm 深度的 0-2-mm、2-6-mm 和 6-10-mm 区域获得 CD。对术后 CD 变化与其他变量（如年龄、手术类型、中央角膜厚度、球镜等效度、微透镜厚度/消融深度以及波前像差变化）进行相关分析。结果：术后 6-12 个月，观察到 FS-LASIK 队列中多个角膜区域显着缩小（P < 0.05）。在 SMILE 队列中，相对于基线，CD 没有观察到显着变化。然而，术后5年，两组三层三个区域的CD均显着下降（均P < 0.001）。术后 6-12 个月，各组之间 CD 的变化相似，但在 5 年时，SMILE 前层和中层的变化幅度明显小于 FS-LASIK（均 P < 0.05）。结论：Scheimpflug 成像系统的 CD 在 SMILE 或 FS-LASIK 术后 5 年显示显着下降，并且在 SMILE 后变化明显不那么明显。
Purpose: To investigate long-term changes in corneal densitometry (CD) following small incision lenticule extraction (SMILE) vs. femtosecond laser-assisted LASIK (FS-LASIK) in patients with myopia or myopic astigmatism. Methods: Prospective analysis was performed in 66 eyes of 38 patients (13 males) who underwent SMILE and 54 eyes of 29 patients (5 males) who underwent FS-LASIK. In all patients, an ocular examination was performed preoperatively, and at 6–12 months and 5 years postoperatively. CD was obtained with the Pentacam Scheimpflug imaging system at the 0–2-mm, 2–6-mm, and 6–10-mm zones of the cornea at depth of anterior 120 μm, midcornea, and posterior 60 μm. Correlation analysis was performed between postoperative change in CD and other variables such as age, type of surgery, central corneal thickness, spherical equivalent, lenticule thickness/ablation depth, and changes in wavefront aberrations. Results: At postoperative 6–12 months, a significant reduction at several corneal zones in the FS-LASIK cohort (P < 0.05) was observed. In the SMILE cohort, no significant change in CD relative to baseline was observed. However, at 5 years postoperatively, in both groups, a significant decrease in CD was observed in three zones of three layers (all P < 0.001). The change in CD was similar between groups at postoperative 6–12 months, but at 5 years the magnitude of change was significantly smaller in SMILE than FS-LASIK in the anterior and central layers (all P < 0.05). Conclusion: CD with the Scheimpflug imaging system showed a significant decrease at 5 years after SMILE or FS-LASIK, and the change was significantly less pronounced after SMILE.
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影响因子：
1.9
作者：
Agca A;Ozgurhan EB;Yildirim Y;Cankaya KI;Guleryuz NB;Alkin Z;Ozkaya A;Demirok A;Yilmaz OF
通讯作者：
Yilmaz OF
影响因子：
4.4
作者：
Sonigo, Bertrand;Iordanidou, Vasiliki;Baudouin, Christophe
通讯作者：
Baudouin, Christophe
影响因子：
1.6
作者：
Garzon, Nuria;Poyales, Francisco;Argueso, Francisco
通讯作者：
Argueso, Francisco
影响因子：
4.2
作者：
Schaub, Friederike;Gerber, Fanny;Bachmann, Bjoern O.
通讯作者：
Bachmann, Bjoern O.
小切口晶状体摘除术 (SMILE) 和飞秒激光原位角膜磨镶术 (FS-LASIK) 后角膜神经支配的共焦比较。
影响因子：
3.7
作者：
Li M;Niu L;Qin B;Zhou Z;Ni K;Le Q;Xiang J;Wei A;Ma W;Zhou X
通讯作者：
Zhou X