Prevalence of and risk factors for high-altitude hyperuricaemia in Bai individuals: a cross-sectional study.
Prevalence of and risk factors for high-altitude hyperuricaemia in Bai individuals: a cross-sectional study.
复制标题
DOI：
10.1177/03000605211028140
复制
发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Chen X
中科院分区：
文献类型：
--
作者：
Gao C;Chen Z;Ma J;Xie J;Zhang W;Ren H;Chen X
高尿酸血症在白族人群中很常见；然而，其流行程度仍不清楚。本研究旨在调查白族人群高原高尿酸血症患病率及其危险因素。所有符合条件的白族受试者（年龄≥18岁，2019年1月至12月在剑川县人民医院常规体检）均连续入组。收集人口统计和实验室数据以调查高尿酸血症患病率和相关危险因素。共有 1393 名参与者接受了评估，其中 345 名 (24.8%) 患有高尿酸血症，男性占主导地位（男性占 287/865 [33.2%]，女性占 58/528 [11.0%]）。年龄≥50岁的参与者（100/332 [30.1%]）的高尿酸血症患病率显着高于30-40岁参与者（59/308 [19.2%]），超重/肥胖个体的高尿酸血症患病率显着高于体重指数不足或正常的参与者（BMI；267/885 [30.2%] vs 78/508 [15.4%]）。最后，血红蛋白浓度与血清尿酸水平呈正相关。除了年龄、性别和体重指数等传统危险因素外，长期暴露在高海拔地区导致的红细胞增多症也可能导致居住在云南白族的高尿酸血症。
Hyperuricaemia is common in Bai individuals; however, its prevalence remains unclear. This work aimed to investigate high-altitude hyperuricaemia prevalence and risk factors in Bai individuals. All eligible participants of Bai ethnicity (aged ≥18 years and undergoing routine medical examination at the People’s Hospital of Jianchuan County between January and December 2019) were consecutively enrolled. Demographic and laboratory data were collected to investigate hyperuricaemia prevalence and associated risk factors. A total of 1393 participants were assessed, comprising 345 (24.8%) with hyperuricaemia showing a male predominance (287/865 [33.2%] males versus 58/528 [11.0%] females). Hyperuricaemia prevalence was significantly higher in participants aged ≥50 years (100/332 [30.1%]) versus those aged 30–40 years (59/308 [19.2%]), and in overweight/obese individuals compared with those showing an underweight or normal body mass index (BMI; 267/885 [30.2%] versus 78/508 [15.4%]). Finally, haemoglobin concentrations and serum uric acid levels were positively correlated. Besides traditional risk factors, including age, sex and BMI, polycythaemia due to prolonged exposure to high altitude may also cause hyperuricaemia in Bai individuals residing in Yunnan Province.
登录
查看更多内容
影响因子：
3.4
作者：
Hurtado-Arestegui, Abdias;Plata-Cornejo, Raul;Pando, Jackelina
通讯作者：
Pando, Jackelina
影响因子：
13.6
作者：
Hurtado Arestegui, Abdias;Fuquay, Richard;Escudero, Elizabeth
通讯作者：
Escudero, Elizabeth
影响因子：
1.6
作者：
Ni, Qun;Lu, Xiaomin;Zhang, Renbing
通讯作者：
Zhang, Renbing
高甘油三酯血症和高尿酸血症：城市居民的回顾性研究
影响因子：
4.5
作者：
Hou, Yan-long;Yang, Xiao-lan;You, Chong-ge
通讯作者：
You, Chong-ge
影响因子：
--
作者：
GORDON, T;KANNEL, WB
通讯作者：
KANNEL, WB