Can the controversial relationship between dietary calcium and body weight be mechanistically explained by alterations in appetite and food intake?

Can the controversial relationship between dietary calcium and body weight be mechanistically explained by alterations in appetite and food intake?
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膳食钙与体重之间存在争议的关系能否通过食欲和食物摄入量的变化来解释?

DOI:
10.1111/j.1753-4887.2008.00111.x
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发表时间:
2008
期刊:
影响因子:
6.1
通讯作者:
Gunther,CarolynW
Gunther,CarolynW
中科院分区:
医学2区
文献类型:
--
作者:
Teegarden,Dorothy;Gunther,CarolynW

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肥胖症的流行已达到世界范围的流行病的比例,超重和肥胖症的发病率继续上升。饮食在调节体重方面起着重要作用,有证据表明钙或乳制品的摄入可能会调节体重和体脂量。已经提出了钙或乳制品可能影响体重或脂肪的几种机制,包括对食欲和食物摄入的可能影响。最近的一项研究调查了人们可以在多大程度上补偿乳制品增加的能量摄入,发现乳制品摄入量增加7天对食欲没有影响,也没有证据表明完全补偿了增加的能量摄入。在另一项研究中,在肥胖受试者中评估了乳制品试验餐中钙含量改变的影响;结果表明,尽管膳食中钙含量较高可降低餐后乳糜微粒相关性高血糖症的程度,但对食欲相关激素(CCK、ghrelin、GLP-1或PPY)或过量自由进食试验餐的能量摄入没有影响。因此,这一新证据并不支持高钙或乳制品摄入会降低食欲或食物摄入量的假设。
The prevalence of obesity has reached epidemic proportions worldwide and the incidence of overweight and obesity continues to rise. Diet plays a significant role in the modulation of body weight and there is some evidence to suggest that calcium or dairy intake may modulate body weight and body fat mass. Several mechanisms through which calcium or dairy products may affect body weight or fat have been suggested, including a possible effect on appetite and food intake. A recent study investigated to what extent people could compensate for increased energy intake from dairy products and found that a 7-day increase in dairy intake had no effect on appetite and no evidence of complete compensation for the raised energy intake. In another study, the effects of altered calcium content of a dairy-based test meal was evaluated in obese subjects; the findings indicated that although a higher calcium content of the meal reduced the extent of post-prandial chylomicron-associated triglyceridemia, there was no effect on appetite-related hormones (CCK, ghrelin, GLP-1, or PPY) or on energy intake from a subsequentad libitumtest meal. Thus, this new evidence does not support the hypothesis that high calcium or dairy intake reduces appetite or food intake.
高膳食钙和维生素 D 对大鼠脂肪量增加和肝酶表达的影响
DOI: --
发表时间: 2007
期刊:
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DOI: 10.1210/jcem.85.12.7063
发表时间: 2000-12
期刊: The Journal of clinical endocrinology and metabolism
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K. Davies;R. Heaney;R. Recker;J. Lappe;M. Barger-Lux;K. Rafferty;S. Hinders
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膳食钙对瘦和肥胖小鼠和大鼠的体重没有影响。
DOI: 10.1152/ajpregu.00655.2003
发表时间: 2004
期刊: American journal of physiology. Regulatory, integrative and comparative physiology
影响因子: --
作者:
Zhang,Qinmin;Tordoff,MichaelG
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增加乳制品消费对食欲和食物摄入量的影响
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发表时间: 2007
期刊: Obesity
影响因子: 6.9
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DOI: 10.2337/diabetes.50.8.1714
发表时间: 2001-08-01
期刊: DIABETES
影响因子: 7.7
作者:
Cummings, DE;Purnell, JQ;Weigle, DS
通讯作者: Weigle, DS