The itchy scalp--scratching for an explanation.

The itchy scalp--scratching for an explanation.
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DOI:
10.1111/j.1600-0625.2011.01389.x
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发表时间:
2011-12
影响因子:
3.6
通讯作者:
Yosipovitch G
Yosipovitch G
中科院分区:
医学2区
文献类型:
--
作者:
Bin Saif GA;Ericson ME;Yosipovitch G

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头皮瘙痒症是一种常见的投诉,被认为是一个诊断和治疗的挑战性的情况。头皮皮肤具有独特的神经结构,包含密集神经支配的毛囊和真皮脉管系统。尽管我们对瘙痒病理生理学的理解最近取得了进展,但头皮瘙痒尚未被研究。在这篇综述中,我们总结了目前的知识,头皮和毛囊的神经生物学以及瘙痒介质,并提供了一个假定的机制,头皮瘙痒,特别强调神经解剖学和病理生理学。
Scalp pruritus is a common complaint that is considered a diagnostically and therapeutically challenging situation. Scalp skin has a unique neural structure that contains densely innervated hair follicles and dermal vasculature. In spite of the recent advances in our understanding of itch pathophysiology, scalp itching has not been studied as yet. In this review, we summarize the current knowledge on the neurobiology of scalp and hair follicles as well as itch mediators and provide a putative mechanism for scalp itch with special emphasis on neuroanatomy and pathophysiology.
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