Impulsivity as a multifactorial construct and its relationship to PTSD severity and threat sensitivity.

Impulsivity as a multifactorial construct and its relationship to PTSD severity and threat sensitivity.
复制标题

冲动是一种多因素构造及其与PTSD严重性和威胁敏感性的关系。

DOI:
10.1016/j.psychres.2020.113468
复制
发表时间:
2020-11
影响因子:
11.3
通讯作者:
Inslicht SS
Inslicht SS
中科院分区:
医学2区
文献类型:
--
作者:
Young DA;Neylan TC;Zhang H;O'Donovan A;Inslicht SS

文献摘要

参考文献

相似文献

DSM-5对创伤后应激障碍(PTSD)概念的改变突出了冲动在PTSD相关唤醒失调背景下的重要性。虽然创伤后应激障碍和威胁敏感性之间的关系已经得到了很好的定义,但它们与冲动性之间的关系仍然没有得到充分研究。我们研究了PTSD症状严重程度、威胁敏感性和冲动性之间的关系。124名参与者完成了PTSD检查表(PCL-C)和Barratt冲动量表第11艾德(BIS-11)。BIS-11项目被分开定义认知和行为冲动子域。一个创伤暴露的子样本39名参与者也暴露于没有,模棱两可的,高威胁的条件下,在一个威胁增强的声音惊吓范式与心理生理反应的结果变量。PTSD严重程度与更大的整体冲动性和行为冲动性显著相关。更大的整体冲动性和认知和行为冲动性子域显着相关的心理生理幅度在创伤的子样本的威胁条件。我们的结果表明,创伤后应激障碍的严重程度可能与行为冲动有关,认知和行为冲动都与威胁敏感性和过度觉醒有关。在PTSD的背景下评估冲动性,特别是在其认知和行为子域方面,可以提供重要的临床相关信息。
Changes to the DSM-5’s conceptualization of posttraumatic stress disorder (PTSD) highlight the importance of impulsivity within the context of PTSD-related arousal dysregulation. While the relationship between PTSD and threat sensitivity is well defined, how they relate to impulsivity remains understudied. We examined the relationship between PTSD symptom severity, threat sensitivity, and impulsivity. 124 participants completed the PTSD Checklist (PCL-C) and the Barratt Impulsiveness Scale 11th ed (BIS-11). BIS-11 items were separated to define cognitive and behavioral impulsivity subdomains. A trauma-exposed subsample of 39 participants were also exposed to no, ambiguous, and high threat conditions in a threat-enhanced acoustic startle paradigm with psychophysiological response as the outcome variable. PTSD severity was significantly associated with greater overall impulsivity and behavioral impulsivity. Greater overall impulsivity and both cognitive and behavioral impulsivity subdomains were significantly associated with psychophysiological magnitudes across threat conditions in the traumatized subsample. Our results suggest PTSD severity may linked to behavioral impulsivity and both cognitive and behavioral impulsivity are associated with threat sensitivity and hyperarousal. Assessing impulsivity within the context of PTSD, particularly in terms of its cognitive and behavioral subdomains, may provide important, clinically relevant information.
DOI: 10.1016/j.neuropharm.2011.02.023
发表时间: 2012-02
期刊: Neuropharmacology
影响因子: 4.7
作者:
Jovanovic T;Kazama A;Bachevalier J;Davis M
通讯作者: Davis M
DOI: 10.1016/j.tics.2010.11.004
发表时间: 2011-02
影响因子: 19.9
作者:
Etkin, Amit;Egner, Tobias;Kalisch, Raffael
通讯作者: Kalisch, Raffael
DOI: 10.1016/j.biopsycho.2016.12.004
发表时间: 2017-02-01
影响因子: 2.6
作者:
Heesink, Lieke;Kleber, Rolf;Geuze, Elbert
通讯作者: Geuze, Elbert
DOI: 10.1037/a0021591
发表时间: 2011-01-01
影响因子: 22.4
作者:
Cross, Catharine P.;Copping, Lee T.;Campbell, Anne
通讯作者: Campbell, Anne
DOI: 10.1001/jamapsychiatry.2019.2102
发表时间: 2019-11-01
期刊: JAMA PSYCHIATRY
影响因子: 25.8
作者:
Amlung, Michael;Marsden, Emma;McCabe, Randi E.
通讯作者: McCabe, Randi E.