SIFTS: Structure Integration with Function, Taxonomy and Sequences resource.

SIFTS: Structure Integration with Function, Taxonomy and Sequences resource.
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DOI:
10.1093/nar/gks1258
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Kleywegt GJ
Kleywegt GJ
中科院分区:
生物学2区
文献类型:
--
作者:
Velankar S;Dana JM;Jacobsen J;van Ginkel G;Gane PJ;Luo J;Oldfield TJ;O'Donovan C;Martin MJ;Kleywegt GJ

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结构与功能、分类学和序列资源整合(SIFTS; http://pdbe.org/sifts)是欧洲蛋白质数据库(PDBe)和UniProt之间的密切合作。这两个团队已经开发了一个半自动化的过程,用于维护UniProt条目的最新交叉引用信息,用于UniProt数据库中PDB条目中的所有蛋白质链。这一过程是为每周的PDB发布而进行的,信息存储在SIFTS数据库中。SIFTS过程包括对其他生物资源的交叉引用,例如Pfam、SCOP、CATH、GO、InterPro和NCBI分类数据库。信息以XML格式导出,每个PDB条目对应一个文件,并通过FTP提供。许多生物信息学资源使用SIFTS数据来获得PDB和其他生物学数据库之间的交叉引用,以便为用户提供最新信息。
The Structure Integration with Function, Taxonomy and Sequences resource (SIFTS; http://pdbe.org/sifts) is a close collaboration between the Protein Data Bank in Europe (PDBe) and UniProt. The two teams have developed a semi-automated process for maintaining up-to-date cross-reference information to UniProt entries, for all protein chains in the PDB entries present in the UniProt database. This process is carried out for every weekly PDB release and the information is stored in the SIFTS database. The SIFTS process includes cross-references to other biological resources such as Pfam, SCOP, CATH, GO, InterPro and the NCBI taxonomy database. The information is exported in XML format, one file for each PDB entry, and is made available by FTP. Many bioinformatics resources use SIFTS data to obtain cross-references between the PDB and other biological databases so as to provide their users with up-to-date information.
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