Indirect measures of cigarette use: expired-air carbon monoxide versus plasma thiocyanate.
Indirect measures of cigarette use: expired-air carbon monoxide versus plasma thiocyanate.
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香烟使用的间接测量:呼出空气一氧化碳与血浆硫氰酸盐。
DOI:
10.1016/0091-7435(84)90045-8
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发表时间:
1984
影响因子:
5.1
通讯作者:
Farquhar,JW
中科院分区:
文献类型:
--
作者:
Fortmann,SP;Rogers,T;Vranizan,K;Haskell,WL;Solomon,DS;Farquhar,JW
Indirect, biochemical measures of cigarette use are valuable in confirming smoking status in both cross-sectional and cessation studies. This study compares two such biochemical markers, expired-air carbon monoxide (CO) and plasma thiocyanate (SCN), in a representative population sample of 2,237 adults (ages 18–74) from the baseline survey of the Stanford Five City Project. CO and SCN are both significantly higher in self-reported smokers than in nonsmokers and correlate well with number of cigarettes smoked per day. CO appears to be more sensitive and specific than SCN in comparison to self-report, and CO misclassifies a significantly smaller number of nonsmokers, regular smokers, and light smokers (<9 cigarettes per day) than does SCN. Together, CO and SCN better classify smokers and nonsmokers than do either alone. Neither biochemical is a reliable indicator in irregular smokers (no cigarettes in past 48 hr). Despite its much shorter metabolic halflife, CO is a better indicator of cigarette use than is SCN in this cross-sectional study. CO is generally simpler and less expensive to measure than is SCN, and CO may be a preferable indirect measure of smoking status in some studies of smoking cessation.
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影响因子:
9.3
作者:
A. Pettigrew;G. Fell
通讯作者:
G. Fell
影响因子:
9.3
作者:
A. Pettigrew;G. Fell
通讯作者:
A. Pettigrew;G. Fell
影响因子:
--
作者:
SILLETT, RW;WILSON, MB;BALL, KP
通讯作者:
BALL, KP
影响因子:
12.7
作者:
J. Cohen;G. Bartsch
通讯作者:
G. Bartsch
影响因子:
12.7
作者:
T. Vogt;S. Selvin;G. Widdowson;S. Hulley
通讯作者:
S. Hulley