Marrow adipose tissue imaging in humans.
Marrow adipose tissue imaging in humans.
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DOI:
10.1016/j.bone.2018.01.009
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发表时间:
2019-01
期刊:
影响因子:
4.1
通讯作者:
Bredella MA
中科院分区:
文献类型:
--
作者:
Singhal V;Bredella MA
Bone strength is affected not only by bone mineral density (BMD) and bone microarchitecture but also its microenvironment. Recent studies have focused on the role of marrow adipose tissue (MAT) in the pathogenesis of bone loss. Osteoblasts and adipocytes arise from a common mesenchymal stem cell within bone marrow and many osteoporotic states, including aging, medication use, immobility, over – and undernutrition are associated with increased marrow adiposity. Advancements in imaging technology allow the non-invasive quantification of MAT. This article will review magnetic resonance imaging (MRI)- and computed tomography (CT)-based imaging technologies to assess the amount and composition of MAT. The techniques that will be discussed are anatomic T1-weighted MRI, water-fat imaging, proton MR spectroscopy, single energy CT and dual energy CT. Clinical applications of MRI and CT techniques to determine the role of MAT in patients with obesity, anorexia nervosa, and type 2 diabetes will be reviewed.
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DOI:
10.1038/oby.2010.106
发表时间:
2011-01
期刊:
Obesity (Silver Spring, Md.)
影响因子:
--
作者:
Bredella MA;Torriani M;Ghomi RH;Thomas BJ;Brick DJ;Gerweck AV;Rosen CJ;Klibanski A;Miller KK
通讯作者:
Miller KK
影响因子:
4.1
作者:
Bredella, Miriam A.;Gerweck, Anu V.;Miller, Karen K.
通讯作者:
Miller, Karen K.
影响因子:
5.5
作者:
Barrett, JF;Keat, N
通讯作者:
Keat, N
影响因子:
4.4
作者:
Cordes, Christian;Dieckmeyer, Michael;Karampinos, Dimitrios C.
通讯作者:
Karampinos, Dimitrios C.
影响因子:
5.2
作者:
Cordes C;Baum T;Dieckmeyer M;Ruschke S;Diefenbach MN;Hauner H;Kirschke JS;Karampinos DC
通讯作者:
Karampinos DC