Effects of Aftermarket Electronic Cigarette Pods on Device Power Output and Nicotine, Carbonyl, and ROS Emissions.

Effects of Aftermarket Electronic Cigarette Pods on Device Power Output and Nicotine, Carbonyl, and ROS Emissions.
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DOI:
10.1021/acs.chemrestox.3c00213
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发表时间:
2023-12-18
影响因子:
4.1
通讯作者:
Shihadeh A
Shihadeh A
中科院分区:
医学3区
文献类型:
--
作者:
Talih S;Karaoghlanian N;Salman R;Hilal E;Patev A;Bell A;Fallah S;El-Hage R;Saliba NA;Cobb C;Barnes A;Shihadeh A

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设计用于与流行的电子尼古丁输送系统(ENDS)产品(如JUUL)一起使用的售后豆荚是作为低成本替代品销售的,允许使用被禁止的调味液体。与原始设备制造商的产品相比,售后豆荚的设计或构造的细微差异可能会从本质上改变ENDS器械的性能以及由此产生的尼古丁和有毒物质排放。在这项研究中,我们检查了JUUL电池的电输出和气溶胶排放,当四个不同品牌的售后豆荚充满了丙二醇,甘油和尼古丁的分析级混合物连接到它和机器膨化。检测的气溶胶排放物包括总颗粒物(TPM)、尼古丁、羰基化合物(CC)和活性氧(ROS)。我们还比较了JUUL和售后市场pod的抽吸解析功率和TPM输出。我们发现,所有售后豆荚在膨化过程中从JUUL电池中消耗的电力明显更大,并且具有不同的电阻和电阻率。此外,与原始pod的情况不同,我们发现,使用售后pod时,电池提供的功率不会随流速或抽吸次数而发生很大变化,这表明与售后pod一起使用时,JUUL器械的温度控制电路受损。更大的功率输出与售后豆荚导致高达三倍以上的气雾剂和尼古丁输出比原来的产品。ROS和CC排放量在不同品牌之间差异很大。这些结果突出表明,使用售后吊舱可以大大改变ENDS的性能和排放。应让消费者和公共卫生当局了解使用售后豆荚时有毒物质暴露水平的潜在增加。
Aftermarket pods designed to operate with prevalent electronic nicotine delivery system (ENDS) products such as JUUL are marketed as low-cost alternatives that allow the use of banned flavored liquids. Subtle differences in the design or construction of aftermarket pods may intrinsically modify the performance of the ENDS device and the resulting nicotine and toxicant emissions relative to the original equipment manufacturer's product. In this study, we examined the electrical output of a JUUL battery and the aerosol emissions when four different brands of aftermarket pods filled with an analytical-grade mixture of propylene glycol, glycerol, and nicotine were attached to it and puffed by machine. The aerosol emissions examined included total particulate matter (TPM), nicotine, carbonyl compounds (CCs), and reactive oxygen species (ROS). We also compared the puff-resolved power and TPM outputs of JUUL and aftermarket pods. We found that all aftermarket pods drew significantly greater electrical power from the JUUL battery during puffing and had different electrical resistances and resistivity. In addition, unlike the case with the original pods, we found that with the aftermarket pods, the power provided by the battery did not vary greatly with flow rate or puff number, suggesting impairment of the temperature control circuitry of the JUUL device when used with the aftermarket pods. The greater power output with the aftermarket pods resulted in up to three times greater aerosol and nicotine output than the original product. ROS and CC emissions varied widely across brands. These results highlight that the use of aftermarket pods can greatly modify the performance and emissions of ENDS. Consumers and public health authorities should be made aware of the potential increase in the level of toxicant exposure when aftermarket pods are employed.
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影响因子: 5.2
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影响因子: 5.2
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DOI: 10.1136/tobaccocontrol-2019-055275
发表时间: 2020-11
期刊: Tobacco control
影响因子: 5.2
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DOI: 10.1093/ntr/ntu174
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影响因子: 4.7
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