Socioeconomic factors, stress, hair cortisol, and white matter microstructure in children.
Socioeconomic factors, stress, hair cortisol, and white matter microstructure in children.
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儿童的社会经济因素，压力，皮质醇和白质微观结构。
DOI：
10.1002/dev.22147
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发表时间：
2021-09
影响因子：
2.2
通讯作者：
Noble, Kimberly G.
中科院分区：
文献类型：
--
作者：
Simon, Katrina R.;Merz, Emily C.;He, Xiaofu;Desai, Pooja M.;Meyer, Jerrold S.;Noble, Kimberly G.
Socioeconomic disadvantage has been linked to increased stress exposure in children and adults. Exposure to stress in childhood has been associated with deleterious effects on cognitive development and well-being throughout the lifespan. Further, exposure to stress has been associated with differences in brain development in children, both in cortical and subcortical gray matter. However, less is known about the associations among socioeconomic disadvantage, stress, and children’s white matter development. In this study, we investigated whether socioeconomic disparities would be associated with differences in white matter microstructure in the cingulum bundle, as has been previously reported. We additionally investigated whether any such differences could be explained by differences in stress exposure and/or physiological stress levels. White matter tracts were measured via diffusion tensor imaging in 58 children aged 5–9 years. Results indicated that greater exposure to stressful life events was associated with higher child hair cortisol concentrations. Further, physiological stress, as indexed by hair cortisol concentrations, were associated with higher fractional anisotropy in the cingulum bundle. These results have implications for better understanding how perceived and physiological stress may alter neural development during childhood.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
4.8
作者：
Catani, Marco
通讯作者：
Catani, Marco
影响因子：
7.2
作者：
Belsky, Jay
通讯作者：
Belsky, Jay
影响因子：
2.2
作者：
Flom M;St John AM;Meyer JS;Tarullo AR
通讯作者：
Tarullo AR
影响因子：
4.6
作者：
Hanson JL;Adluru N;Chung MK;Alexander AL;Davidson RJ;Pollak SD
通讯作者：
Pollak SD