Direct electrical stimulation of the somatosensory cortex in humans using electrocorticography electrodes: a qualitative and quantitative report.
Direct electrical stimulation of the somatosensory cortex in humans using electrocorticography electrodes: a qualitative and quantitative report.
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DOI：
10.1088/1741-2560/10/3/036021
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发表时间：
2013-06
影响因子：
4
通讯作者：
Ojemann JG
中科院分区：
文献类型：
--
作者：
Johnson LA;Wander JD;Sarma D;Su DK;Fetz EE;Ojemann JG
最近，基于皮层电图的脑机接口已成功用于将皮层活动转化为外部设备的控制信号。然而，体感反馈将大大增强此类设备的实用性。体感皮层的直接刺激会唤起感官知觉，因此是闭合循环的一个有前途的选择。在将其应用于人类之前，有必要评估如何感知刺激参数的变化以及它们可以被区分的程度。电刺激被传送到植入皮质电图网格的人类受试者的体感皮层。受试者被要求区分不同频率和幅度的刺激，并报告刺激引起的定性感觉。在这项研究中，我们表明，在植入皮质电图网格的人类中，皮质电刺激的幅度或频率的变化会产生感知的分级变化。受试者能够可靠地区分不同的刺激。这些结果表明直接皮层刺激是脑机接口设备感觉反馈的可行选择。
Recently, electrocorticography-based brain-computer interfaces have been successfully used to translate cortical activity into control signals for external devices. However, the utility of such devices would be greatly enhanced by somatosensory feedback. Direct stimulation of somatosensory cortex evokes sensory perceptions, and is thus a promising option for closing the loop. Before this can be implemented in humans it is necessary to evaluate how changes in stimulus parameters are perceived and the extent to which they can be discriminated. Electrical stimulation was delivered to the somatosensory cortex of human subjects implanted with electrocorticography grids. Subjects were asked to discriminate between stimuli of different frequency and amplitude as well as to report the qualitative sensations elicited by the stimulation. In this study we show that in humans implanted with electrocorticography grids, variations in the amplitude or frequency of cortical electrical stimulation produce graded variations in percepts. Subjects were able to reliably distinguish between different stimuli. These results indicate that direct cortical stimulation is a feasible option for sensory feedback with brain-computer interface devices.
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影响因子：
2.9
作者：
Antal, Andrea;Brepohl, Nadine;Paulus, Walter
通讯作者：
Paulus, Walter
影响因子：
3.4
作者：
Rogalewski, A;Breitenstein, C;Knecht, S
通讯作者：
Knecht, S
影响因子：
4.7
作者：
Bachmann, Cornelius G.;Muschinsky, Sebastian;Happe, Svenja
通讯作者：
Happe, Svenja
影响因子：
3.5
作者：
O'Doherty, Joseph E.;Lebedev, Mikhail A.;Nicolelis, Miguel A. L.
通讯作者：
Nicolelis, Miguel A. L.
影响因子：
4.1
作者：
HAGLUND, MM;OJEMANN, GA;BLASDEL, GG
通讯作者：
BLASDEL, GG