Oxytocin increases eye-gaze towards novel social and non-social stimuli.
Oxytocin increases eye-gaze towards novel social and non-social stimuli.
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催产素增加了人们对新型社会和非社会刺激的目光。
DOI：
10.1080/17470919.2018.1542341
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发表时间：
2019-10
影响因子：
2
通讯作者：
Ditzen B
中科院分区：
文献类型：
--
作者：
Eckstein M;Bamert V;Stephens S;Wallen K;Young LJ;Ehlert U;Ditzen B
对催产素(OT)的研究揭示了这种神经肽在社会认知过程和依恋行为中的重要作用。本项目的基本原理是破译OT在人类受试者对非性爱依恋刺激和生殖相关刺激的基本社会认知过程中的差异作用。在随机双盲重复交叉设计中，N=82名参与者被调查了两次，并在第一次评估时接受鼻内催产素或安慰剂，在第二次评估时接受安慰剂或安慰剂。研究人员向参与者展示了标准的亲子二人组图片、正在进行非性爱或露骨的性行为的浪漫情侣图片，以及非社交图片，同时我们评估了瞳孔放大和眼睛聚焦于特定的预先定义的感兴趣区域。多水平的分析表明，在最初的陈述中，OT增加了对所有类别刺激的瞳孔放大，并导致眼睛集中在眼睛和身体区域，随后在第二次会议上，瞳孔放大和凝视显著减少。这些遗留效应表明，在最初接触社会刺激时进行的激素治疗可以决定这些刺激后来是如何处理的。这些结果可能对催产素作为反复接触社会材料的干预措施的治疗有影响。
Research on oxytocin (OT) has revealed a substantial involvement of this neuropeptide in social cognition processes and attachment behavior. The rationale of the present project was to decipher the differential role of OT in basic social cognition processes towards non-erotic attachment stimuli vs. reproduction-related stimuli in human subjects. In a randomized double-blind repeated-measures cross-over design, N = 82 participants were investigated twice and received either intranasal OT or placebo at the first assessment followed by placebo or OT at second assessment. Participants were presented with standardized pictures of parent-child dyads, romantic couples engaging in non-erotic or explicit sexual activities, and non-social pictures while we assessed pupil dilation and eye focus on specific pre-defined areas of interest. Multilevel analyses suggest that during the initial presentation, OT increased pupil dilation towards all categories of stimuli and led the eye focus towards the eyes and body regions, followed by a strong decrease in pupil dilation and fixations at the second session. These carry-over effects indicate that hormonal treatment at an initial contact to social stimuli can determine how these stimuli are processed later. These results might have implications for OT as a treatment in interventions with repeated exposure to social material.
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影响因子：
3.7
作者：
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通讯作者：
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影响因子：
6.8
作者：
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通讯作者：
Baron-Cohen S