Inhibition of proliferation of cultured rat liver epithelial cells at specific cell cycle stages by transforming growth factor-beta.

Inhibition of proliferation of cultured rat liver epithelial cells at specific cell cycle stages by transforming growth factor-beta.
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通过转化生长因子-β 抑制培养的大鼠肝上皮细胞在特定细胞周期阶段的增殖。

DOI:
10.1016/0006-291x(87)90624-3
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发表时间:
1987
影响因子:
3.1
通讯作者:
Grisham,JW
Grisham,JW
中科院分区:
生物学4区
文献类型:
--
作者:
Lin,P;Liu,C;Tsao,MS;Grisham,JW

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转化生长因子-β(transforminggrowthfactor-β,TGF-β)可明显抑制正常成年大鼠肝上皮细胞增殖。抑制作用是完全可逆的,在细胞周期的两个不同点,即G1 S边界和G 0或早期G1期受到影响。随着培养物中传代次数的增加,肝上皮细胞对TGF-β的抑制作用逐渐变得不敏感。
Proliferation of early-passage propagable cultured rat liver epithelial cells derived from normal adult rats is markedly inhibited by transforming growth factor-β (TGF-β). Inhibition, which is completely reversible, is effected at two distinct points of the cell cycle, the G 1 S border and the G 0 or early G 1 phase. With increasing passages in culture, hepatic epithelial cells progressively become less sensitive to the inhibitory effect of TGF-β.
DOI: 10.1126/science.3461562
发表时间: 1986-09-05
期刊: SCIENCE
影响因子: 56.9
作者:
HEIMARK, RL;TWARDZIK, DR;SCHWARTZ, SM
通讯作者: SCHWARTZ, SM
二倍体大鼠肝细胞株的长期培养 *
DOI: 10.1111/j.1749-6632.1980.tb29524.x
发表时间: 1980
影响因子: 5.2
作者:
W. Schaeffer
通讯作者: W. Schaeffer
DOI: 10.1016/0014-4827(71)90316-8
发表时间: 1971-01-01
影响因子: 3.7
作者:
WILLIAMS, GM;WEISBURGER, EK;WEISBURGER, JH
通讯作者: WEISBURGER, JH
转化生长因子-β对培养的正常和恶性大鼠肝上皮细胞增殖的不同影响。
DOI: --
发表时间: 1986
期刊: Cancer Research
影响因子: 11.2
作者:
McMahon Jb;Richards Wl;del Campo Aa;Min Song;S. Thorgeirsson
通讯作者: S. Thorgeirsson
DOI: 10.1016/0014-4827(84)90666-9
发表时间: 1984-01-01
影响因子: 3.7
作者:
TSAO, MS;SMITH, JD;GRISHAM, JW
通讯作者: GRISHAM, JW