Trunk exoskeleton in teleosts is mesodermal in origin.
Trunk exoskeleton in teleosts is mesodermal in origin.
复制标题
DOI：
10.1038/ncomms2643
复制
发表时间：
2013
影响因子：
16.6
通讯作者：
中科院分区：
文献类型：
--
作者：
已知的脊椎动物矿化骨骼最初是作为外骨骼出现的，它广泛地覆盖了无颌鱼的化石。这种外骨骼的进化起源长期以来一直被归因于神经脊的出现，但对此的实验评估仍然很差。在这里，我们通过应用长期细胞标记方法确定青竹(硬骨鱼躯干外骨骼)鳞片和鳍条的胚胎起源，并证明这两种组织都是中胚层起源。然而，神经脊细胞无法为这些组织做出贡献。这一结果表明，鱼类的躯干神经脊不具有成骨能力，而是突出了中胚层在躯干骨骼进化中的主导作用。这进一步表明，从脊椎动物进化的早期起，神经脊在骨骼形成中的作用就一直在头骨区域占据主导地位。非四足动物的躯干外骨骼元素，如鳞片和鳍条，被认为来自神经脊。Shimada和他的同事使用长期细胞标记方法来证明这些元素实际上来自中胚层。
The vertebrate mineralized skeleton is known to have first emerged as an exoskeleton that extensively covered the fossil jawless fish. The evolutionary origin of this exoskeleton has long been attributed to the emergence of the neural crest, but experimental evaluation for this is still poor. Here we determine the embryonic origin of scales and fin rays of medaka (teleost trunk exoskeletons) by applying long-term cell labelling methods, and demonstrate that both tissues are mesodermal in origin. Neural crest cells, however, fail to contribute to these tissues. This result suggests that the trunk neural crest has no skeletogenic capability in fish, instead highlighting the dominant role of the mesoderm in the evolution of the trunk skeleton. This further implies that the role of the neural crest in skeletogenesis has been predominant in the cephalic region from the early stage of vertebrate evolution. Trunk exoskeleton elements of non-tetrapods such as scales and fin rays are believed to derive from the neural crest. Shimada and colleagues use long-term cell labelling methods to show that these elements are actually derived from the mesoderm.
登录
查看更多内容
影响因子：
64.8
作者：
Freitas, Renata;Zhang, GuangJun;Cohn, Martin J.
通讯作者：
Cohn, Martin J.
影响因子：
2.5
作者：
Deguchi, Tomonori;Itoh, Mariko;Kamei, Yasuhiro
通讯作者：
Kamei, Yasuhiro
影响因子：
64.5
作者：
Nakashima, K;Zhou, X;de Crombrugghe, B
通讯作者：
de Crombrugghe, B
影响因子：
2.7
作者：
Jiang, XB;Iseki, S;Morriss-Kay, GM
通讯作者：
Morriss-Kay, GM
影响因子：
48
作者：
Kamei, Yasuhiro;Suzuki, Motoshi;Yuba, Shunsuke
通讯作者：
Yuba, Shunsuke