Infant fMRI: A Model System for Cognitive Neuroscience.

Infant fMRI: A Model System for Cognitive Neuroscience.
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DOI:
10.1016/j.tics.2018.01.005
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发表时间:
2018-05
影响因子:
19.9
通讯作者:
Turk-Browne NB
Turk-Browne NB
中科院分区:
心理学1区
文献类型:
--
作者:
Ellis CT;Turk-Browne NB

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我们对典型人类大脑的理解很大程度上得益于对不同类型的大脑及其相关行为的研究,包括动物模型和神经心理学患者。同样的比较视角也可以应用于早期发育——婴儿的环境、行为和大脑为理解成熟的大脑如何工作提供了一个模型系统。这种方法需要非侵入性的方法来测量清醒、行为正常的婴儿的大脑功能。fMRI在这方面正变得越来越可行,它具有精确测量整个大脑的独特能力,包括皮层和皮层下结构。在这里,我们讨论了婴儿功能磁共振成像对成人认知的几个领域的潜在教训,并考虑了进行此类研究的挑战以及如何减轻这些挑战。
Our understanding of the typical human brain has benefitted greatly from studying different kinds of brains and their associated behavioral repertoires, including animal models and neuropsychological patients. This same comparative perspective can be applied to early development — the environment, behavior, and brains of infants provide a model system for understanding how the mature brain works. This approach requires non-invasive methods for measuring brain function in awake, behaving infants. fMRI is becoming increasingly viable for this purpose, with the unique ability to precisely measure the entire brain, including both cortical and subcortical structures. Here we discuss potential lessons from infant fMRI for several domains of adult cognition and consider the challenges of conducting such research and how they might be mitigated.
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