Substance use patterns in 9-10 year olds: Baseline findings from the adolescent brain cognitive development (ABCD) study.
Substance use patterns in 9-10 year olds: Baseline findings from the adolescent brain cognitive development (ABCD) study.
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DOI：
10.1016/j.drugalcdep.2021.108946
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发表时间：
2021-10-01
影响因子：
4.2
通讯作者：
ABCD Consortium
中科院分区：
文献类型：
--
作者：
Lisdahl KM;Tapert S;Sher KJ;Gonzalez R;Nixon SJ;Feldstein Ewing SW;Conway KP;Wallace A;Sullivan R;Hatcher K;Kaiver C;Thompson W;Reuter C;Bartsch H;Wade NE;Jacobus J;Albaugh MD;Allgaier N;Anokhin AP;Bagot K;Baker FC;Banich MT;Barch DM;Baskin-Sommers A;Breslin FJ;Brown SA;Calhoun V;Casey BJ;Chaarani B;Chang L;Clark DB;Cloak C;Constable RT;Cottler LB;Dagher RK;Dapretto M;Dick A;Do EK;Dosenbach NUF;Dowling GJ;Fair DA;Florsheim P;Foxe JJ;Freedman EG;Friedman NP;Garavan HP;Gee DG;Glantz MD;Glaser P;Gonzalez MR;Gray KM;Grant S;Haist F;Hawes S;Heeringa SG;Hermosillo R;Herting MM;Hettema JM;Hewitt JK;Heyser C;Hoffman EA;Howlett KD;Huber RS;Huestis MA;Hyde LW;Iacono WG;Isaiah A;Ivanova MY;James RS;Jernigan TL;Karcher NR;Kuperman JM;Laird AR;Larson CL;LeBlanc KH;Lopez MF;Luciana M;Luna B;Maes HH;Marshall AT;Mason MJ;McGlade E;Morris AS;Mulford C;Nagel BJ;Neigh G;Palmer CE;Paulus MP;Pecheva D;Prouty D;Potter A;Puttler LI;Rajapakse N;Ross JM;Sanchez M;Schirda C;Schulenberg J;Sheth C;Shilling PD;Sowell ER;Speer N;Squeglia L;Sripada C;Steinberg J;Sutherland MT;Tomko R;Uban K;Vrieze S;Weiss SRB;Wing D;Yurgelun-Todd DA;Zucker RA;Heitzeg MM;ABCD Consortium
青少年大脑认知发展™研究（ABCD研究Ⓡ）是一项开放科学、多地点、前瞻性、纵向研究，追踪超过11800名9岁和10岁的青少年进入成年早期。ABCD研究旨在前瞻性研究物质使用（SU）对神经认知和健康结果的影响。虽然SU通常发生在青少年时期，但对12岁以下儿童的SU模式知之甚少。本研究旨在报告详细的ABCD研究Ⓡ基线（n=11,875） SU模式，以便为更大的科学界提供有关队列早期SU的信息。随着SU的详细描述，我们运行混合效应回归模型，以检查早期咖啡因和酒精饮用与人口因素，外化症状和父母酒精和物质使用障碍史（AUD/SUD）之间的关系。在基线时，大多数年轻人使用咖啡因（67.6%），22.5%的人报告饮用酒精（22.5%）。几乎没有报告使用其他药物类别（0.2%全酒精饮料，0.7%使用尼古丁，0.1%使用大麻，<0.02%使用任何其他滥用药物）。分析显示，总咖啡因用量和早期饮酒与人口统计学变量（p < 0.05）、外化症状（咖啡因p=0002；啜饮p= 0.0003）和父母的AUD病史（啜饮p= 0.03）相关。9-10岁的ABCD研究参与者报告了咖啡因使用和饮酒实验，但很少有其他的SU。在未来的纵向分析中，ABCD研究队列中，与儿童早期饮酒和咖啡因使用相关的变量应该作为SU升级轨迹的影响因素进行研究。
The Adolescent Brain Cognitive Development ™ Study (ABCD StudyⓇ) is an open-science, multi-site, prospective, longitudinal study following over 11,800 9- and 10-year-old youth into early adulthood. The ABCD Study aims to prospectively examine the impact of substance use (SU) on neurocognitive and health outcomes. Although SU initiation typically occurs during teen years, relatively little is known about patterns of SU in children younger than 12. This study aims to report the detailed ABCD StudyⓇSU patterns at baseline (n=11,875) in order to inform the greater scientific community about cohort’s early SU. Along with a detailed description of SU, we ran mixed effects regression models to examine the association between early caffeine and alcohol sipping with demographic factors, externalizing symptoms and parental history of alcohol and substance use disorders (AUD/SUD). At baseline, the majority of youth had used caffeine (67.6%) and 22.5% reported sipping alcohol (22.5%). There was little to no reported use of other drug categories (0.2% full alcohol drink, 0.7% used nicotine, 0.1% used cannabis, <0.02% used any other drug of abuse). Analyses revealed that total caffeine use and early alcohol sipping were associated with demographic variables (p’s<.05), externalizing symptoms (caffeine p=0002; sipping p=.0003), and parental history of AUD (sipping p=.03). ABCD Study participants aged 9–10 years old reported caffeine use and alcohol sipping experimentation, but very rare other SU. Variables linked with early childhood alcohol sipping and caffeine use should be examined as contributing factors in future longitudinal analyses examining escalating trajectories of SU in the ABCD Study cohort.
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DOI：
10.1073/pnas.0402680101
发表时间：
2004-05-25
影响因子：
11.1
作者：
Gogtay, N;Giedd, JN;Thompson, PM
通讯作者：
Thompson, PM
影响因子：
4.7
作者：
Iacono WG;Heath AC;Hewitt JK;Neale MC;Banich MT;Luciana MM;Madden PA;Barch DM;Bjork JM
通讯作者：
Bjork JM
影响因子：
4
作者：
Gardner, M;Steinberg, L
通讯作者：
Steinberg, L
影响因子：
4.7
作者：
Casey BJ;Cannonier T;Conley MI;Cohen AO;Barch DM;Heitzeg MM;Soules ME;Teslovich T;Dellarco DV;Garavan H;Orr CA;Wager TD;Banich MT;Speer NK;Sutherland MT;Riedel MC;Dick AS;Bjork JM;Thomas KM;Chaarani B;Mejia MH;Hagler DJ Jr;Daniela Cornejo M;Sicat CS;Harms MP;Dosenbach NUF;Rosenberg M;Earl E;Bartsch H;Watts R;Polimeni JR;Kuperman JM;Fair DA;Dale AM;ABCD Imaging Acquisition Workgroup
通讯作者：
ABCD Imaging Acquisition Workgroup
影响因子：
6.6
作者：
Casey, B. J.;Getz, Sarah;Galvan, Adriana
通讯作者：
Galvan, Adriana