Defensive responses of Brandt's voles (Lasiopodomys brandtii) to chronic predatory stress
Defensive responses of Brandt's voles (Lasiopodomys brandtii) to chronic predatory stress
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布氏田鼠（Lasiopodomysbrandtii）对慢性捕食应激的防御反应
DOI：
10.1016/j.physbeh2013.12.001
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发表时间：
2014-03
影响因子：
2.9
通讯作者：
Wei Wanhong
中科院分区：
文献类型：
--
作者：
Hegab Ibrahim M.;Shang Guoshen;Ye Manhong;Jin Yajuan;Wang Aiqin;Yin Baofa;Yang Shengmei;Wei Wanhong
Predator odors are non-intrusive natural stressors of high ethological relevance. The objective of this study was to investigate the processing of a chronic, life-threatening stimulus during repeated prolonged presentation to Brandt's voles. One hundred and twenty voles were tested by repeated presentation of cat feces in a defensive withdrawal apparatus. Voles exposed to feces for short periods showed more avoidance, more concealment in the hide box, less contact time with the odor source, more freezing behavior, less grooming, more jumping, and more vigilant rearing than did non-exposed voles, and those exposed for longer periods. Serum levels of adrenocorticotropic hormone and corticosterone increased significantly when animals were repeatedly exposed to cat feces for short periods. The behavioral and endocrine responses habituated during prolonged presentation of cat feces. ΔfosBmRNA expression level was highest in voles exposed to cat feces for 6 and 12 consecutive days, and subsequently declined in animals exposed to cat feces for 24 days. We therefore conclude that the behavioral and endocrine responses to repeated exposure to cat feces undergo a process of habituation, while ΔfosBchanges in the medial hypothalamic region exhibit sensitization. We propose that habituation and sensitization are complementary rather than contradictory processes that occur in the same individual upon repeated presentation of the same stressor.
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影响因子：
3.3
作者：
Nakadate, K.;Imamura, K.;Watanabe, Y.
通讯作者：
Watanabe, Y.
影响因子：
2.9
作者：
Alibhai, Imran N.;Green, Thomas A.;Nestler, Eric J.
通讯作者：
Nestler, Eric J.
影响因子：
2.9
作者：
FILE, SE;ZANGROSSI, H;MABBUTT, PS
通讯作者：
MABBUTT, PS
影响因子：
8.2
作者：
Apfelbach, R;Blanchard, CD;McGregor, IS
通讯作者：
McGregor, IS
DOI：
10.1016/j.pnpbp.2003.09.012
发表时间：
2003-12-01
影响因子：
5.6
作者：
Blanchard, DC;Griebel, G;Blanchard, RJ
通讯作者：
Blanchard, RJ