A comparison of arsenic exposure in young children and home water arsenic in two rural West Texas communities.
A comparison of arsenic exposure in young children and home water arsenic in two rural West Texas communities.
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DOI：
10.1186/s12889-017-4808-4
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发表时间：
2017-10-27
影响因子：
4.5
通讯作者：
Sobin C
中科院分区：
文献类型：
--
作者：
Del Rio M;Alvarez J;Mayorga T;Dominguez S;Sobin C
在以前进行的健康影响评估的井水依赖西南社区，砷（As）水平大于EPA最大污染物水平（10微克/升）被确定在家庭水样。本研究的目的是测试是否儿童从以前研究的井水依赖社区（社区1）有较高的血液As水平比儿童从人口统计学上类似的和地理上邻近的社区依赖于市政供水（社区2），以测试是否家庭水As水平预测儿童作为血液水平，并检查如何儿童作为血液水平随时间变化。这是一项对来自两个社区的252名4至12岁儿童的观察性研究。通过小学招募儿童，并在上学期间进行测试; 204名儿童参加了后续测试。根据美国环境保护署推荐的程序收集家庭水样。采用电感耦合等离子体质谱法分析儿童血液重金属水平和家庭水样重金属水平。一般线性回归分析被用来测试社区对儿童砷水平的影响，并检查家庭水砷水平的儿童血砷水平的贡献。在所有接受测试的儿童中均可检测到砷。血液水平范围为0.09-2.61 μg/dL;在时间I检测的儿童中，约31%（79/252）的血液As值高于当前可接受限值（1.2 μg/dL）。约8%的家庭水样（6/76）的砷含量高于10 μg/L。社区没有预测儿童血砷水平;季节性影响不同的社区。在时间II，儿童血砷水平高于社区2比社区1。在接受测试的社区中，很大一部分儿童接触过砷。家庭水砷水平不能预测儿童血液砷水平。随着季节和时间的推移，儿童血液As水平的波动表明多种因素的贡献，需要进一步研究。
In a previously conducted Health Impact Assessment of a well-water dependent southwest community, arsenic (As) levels greater than the EPA Maximum Contaminant Level (10 μg/L) were identified in home water samples. The goals of this study were to test whether children from the previously studied well-water dependent community (Community 1) had higher blood As levels than children from a demographically similar and geographically nearby community dependent on a municipal water supply (Community 2); to test whether home water As levels predicted child As blood levels; and to examine how child As blood levels changed over time. This was an observational study of 252 children aged 4 to 12 years from two communities. Children were recruited through elementary schools and tested during the school day; 204 children participated in follow-up testing. Home water samples were collected according to U.S. Environmental Protection agency recommended procedures. Child heavy metal blood levels and home water sample heavy metal levels were analyzed using inductively coupled plasma mass spectrometry. General linear regression analysis was used to test the influence of community on child As levels, and to examine the contribution of home water As levels to child blood As levels. Arsenic was detectable in all children tested. Blood levels ranged from 0.09–2.61 μg/dL; approximately 31% of children tested at Time I (79/252) had blood As values above the current acceptable limit (1.2 μg/dL). Approximately 8% of household water samples (6/76) had As levels higher than 10 μg/L. Community did not predict child blood As levels; seasonal effects differed by Community. At Time II, child blood As levels were higher in Community 2 than in Community 1. A large proportion of children in the communities tested had As exposure. Home water As levels did not predict child blood As levels. Fluctuating child blood As levels by season and over time suggested the contribution of multiple factors and the need for further studies.
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影响因子：
10.4
作者：
Gollenberg AL;Hediger ML;Lee PA;Himes JH;Louis GM
通讯作者：
Louis GM
影响因子：
8.3
作者：
Calderón, J;Navarro, ME;Díaz-Barriga, F
通讯作者：
Díaz-Barriga, F
影响因子：
7.7
作者：
Hamadani, J. D.;Tofail, F.;Vahter, M.
通讯作者：
Vahter, M.
影响因子：
10.4
作者：
de Burbure C;Buchet JP;Leroyer A;Nisse C;Haguenoer JM;Mutti A;Smerhovsky Z;Cikrt M;Trzcinka-Ochocka M;Razniewska G;Jakubowski M;Bernard A
通讯作者：
Bernard A
影响因子：
10.4
作者：
Parvez F;Wasserman GA;Factor-Litvak P;Liu X;Slavkovich V;Siddique AB;Sultana R;Sultana R;Islam T;Levy D;Mey JL;van Geen A;Khan K;Kline J;Ahsan H;Graziano JH
通讯作者：
Graziano JH