Analysis of 1-Minute Potentially Available Fluoride from Dentifrice.
Analysis of 1-Minute Potentially Available Fluoride from Dentifrice.
复制标题
DOI：
10.6028/jres.119.025
复制
发表时间：
2014-12-04
影响因子：
1.5
通讯作者：
Schmuck BD
中科院分区：
文献类型：
--
作者：
Carey CM;Holahan EC;Schmuck BD
以前的报告发现，一些含氟牙膏在刷牙时不会释放有效浓度的氟化物。未能释放氟化物可能是由于在刷牙期间干扰氟化物盐溶解的可吸收基质组分。新一代的牙膏具有在刷牙过程中沉淀有益的氟化物盐的能力。因此，需要一种评估1分钟刷牙期间潜在可用氟化物的方法。为了满足这一需求，开发了一种新的滤纸吸收法来评估1分钟生物可利用氟化物浓度。该方法利用盘绕的滤纸，其快速吸收悬浮液的水相，然后离心以回收该流体用于经由氟离子选择性电极的氟测量。该分析方法被用来成功地确定总氟和1分钟的生物可利用氟在8个可吸收的产品含有氟化钠（NaF），单氟磷酸二钠（Na2FPO3，MFP），氟化亚锡（SnF2），或NaF与无定形磷酸钙（NaF + ACP）。结果表明，一些被测土壤的潜在有效氟含量明显低于总氟含量。对于含有MFP的样品，老化超过其有效期7年，与未老化的MFP产品相比，生物可利用的氟化物显着减少。除老化MFP和含SnF2样品外，所有供试产品的生物可利用氟化物浓度至少为标签氟化物浓度的80%。滤纸吸收法得到的MFP样品测试产品的结果具有重现性，显示出最大的变化。
Previous reports found that some fluoride-containing dentifrices do not release effective concentrations of fluoride during brushing. Failure to release fluoride can be due to dentifrice matrix components that interfere with the solubilization of the fluoride salts during brushing. A new generation of dentifrices has the capability to precipitate beneficial fluoride salts during tooth brushing. Therefore, a method that assesses the potentially available fluoride during the 1-minute brushing is needed. A new filter-paper absorption method to assess the 1-min bioavailable fluoride concentration was developed to meet this need. This method utilizes coiled filter paper that rapidly absorbs the aqueous phase of the dentifrice slurry followed by centrifugation to recover that fluid for fluoride measurement via fluoride ion-selective electrode. The analytical method was used to successfully determine the total fluoride and 1-min bioavailable fluoride in eight dentifrice products containing sodium fluoride (NaF), disodium monofluorophosphate (Na2FPO3, MFP), stannous fluoride (SnF2), or NaF with amorphous calcium phosphate (NaF + ACP). The results showed that some of the dentifrices tested had significantly lower potentially available fluoride than the total fluoride. For a MFP-containing sample, aged seven years past its expiry date, there was significant reduction in the bioavailable fluoride compared to MFP products that were not aged. Other than the aged MFP and the SnF2-containing samples the bioavailable fluoride for all products tested had at least 80 % of the label fluoride concentration. The filter paper absorption method yielded reproducible results for the products tested with MFP samples showing the largest variations.
登录
查看更多内容
影响因子：
4.2
作者：
VONDERFEHR, FR;MOLLER, IJ
通讯作者：
MOLLER, IJ
影响因子：
--
作者：
Cury, Jaime Aparecido;Oliveira, Maria José Lages de;Paiva, Saul Martins
通讯作者：
Paiva, Saul Martins
影响因子：
4.4
作者：
HATTAB, FN
通讯作者：
HATTAB, FN
DOI：
10.1159/000325166
发表时间：
2011-01-01
期刊：
FLUORIDE AND THE ORAL ENVIRONMENT
影响因子：
--
作者：
Vogel, Gerald Lee
通讯作者：
Vogel, Gerald Lee
DOI：
10.1177/00220345550340040701
发表时间：
1955-01-01
期刊：
JOUR DENTAL RES
影响因子：
--
作者：
LILIENTHAL, B.
通讯作者：
LILIENTHAL, B.