Phages preying on Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis: past, present and future.
Phages preying on Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis: past, present and future.
复制标题
DOI：
10.3390/v6072623
复制
发表时间：
2014-07-09
期刊：
影响因子：
--
通讯作者：
Mahillon J
中科院分区：
文献类型：
--
作者：
Gillis A;Mahillon J
许多噬菌体（噬菌体）因其在细菌病原体毒力进化中的重要作用而被广泛研究。然而，人们对捕食蜡状芽孢杆菌群细菌的噬菌体关注较少，并且它们对细菌遗传库的贡献也被忽视。因此，这篇综述汇集了蜡样芽胞杆菌噬菌体的主要信息，从它们的发现到现代生物技术应用。特别关注感染炭疽芽孢杆菌、蜡状芽孢杆菌和苏云金芽孢杆菌的噬菌体。这些噬菌体属于肌病毒科、Siphoviridae、Podoviridae 和 Tectiviridae 科。为了清楚起见，根据生活方式和溶原状态等重要特征划分了几种噬菌体类别。主要类别包括转导噬菌体、具有染色体或质粒原噬菌体状态的噬菌体、γ样噬菌体和巨型噬菌体。本工作还讨论了其中一些噬菌体的当前基因组特征，并在此讨论了一些有前途的应用。
Many bacteriophages (phages) have been widely studied due to their major role in virulence evolution of bacterial pathogens. However, less attention has been paid to phages preying on bacteria from the Bacillus cereus group and their contribution to the bacterial genetic pool has been disregarded. Therefore, this review brings together the main information for the B. cereus group phages, from their discovery to their modern biotechnological applications. A special focus is given to phages infecting Bacillus anthracis, B. cereus and Bacillus thuringiensis. These phages belong to the Myoviridae, Siphoviridae, Podoviridae and Tectiviridae families. For the sake of clarity, several phage categories have been made according to significant characteristics such as lifestyles and lysogenic states. The main categories comprise the transducing phages, phages with a chromosomal or plasmidial prophage state, γ-like phages and jumbo-phages. The current genomic characterization of some of these phages is also addressed throughout this work and some promising applications are discussed here.
登录
查看更多内容
影响因子：
5.3
作者：
Bandara, Nadeeka;Jo, Junhee;Kim, Kwang-Pyo
通讯作者：
Kim, Kwang-Pyo
影响因子：
2.8
作者：
ACKERMANN, HW;ROY, R;SMIRNOFF, WA
通讯作者：
SMIRNOFF, WA
影响因子：
4.4
作者：
ARONSON, AI;BECKMAN, W
通讯作者：
BECKMAN, W
影响因子：
3.8
作者：
BAER, BS;KRUEGER, AP
通讯作者：
KRUEGER, AP
影响因子：
3.7
作者：
Barylski J;Nowicki G;Goździcka-Józefiak A
通讯作者：
Goździcka-Józefiak A