Streptococcus mutans and Streptococcus sanguinis colonization correlated with caries experience in children.
Streptococcus mutans and Streptococcus sanguinis colonization correlated with caries experience in children.
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作者：
Ge Y;Caufield PW;Fisch GS;Li Y
本研究的目的是研究口腔中变形链球菌和血链球菌的定殖及其与儿童早期重度龋（S-ECC）的关系。收集14名S-ECC儿童和8名无龋（CF）儿童的唾液和菌斑样本。所有S-ECC患儿均为S。CF组100%和S-ECC组93%为变形链球菌。血细胞阳性。儿童龋病的严重程度与S.变形链球菌（P<0.001）、口腔链球菌总数（P<0.01）、口腔细菌培养总数（P<0.05）和儿童年龄（P<0.05）。Logistic回归分析表明，S. sanguinis与S.变形菌是儿童龋病发生的重要因素，提示口腔中这两种微生物的相对水平在龋病发生中起重要作用。
The aim of this study was to examine the colonization of Streptococcus mutans and Streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (S-ECC). Saliva and plaque samples were collected from 14 S-ECC children and 8 caries free (CF) children. All S-ECC children were S. mutans positive; 100% CF children and 93% of S-ECC children were S. sanguinis positive. The children’s caries severity was positively correlated with levels of S. mutans (p<0.001), total oral streptococci (p<0.01), total cultivable oral bacteria (p<0.05), and children’s age (p<0.05). Logistic regression analysis showed that the interaction of S. sanguinis with S. mutans were significant factors associated with the caries status in children, suggesting that the relative levels of these two microorganisms in the oral cavity play an important role in caries development.
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影响因子：
3
作者：
Okada, M;Soda, Y;Kozai, K
通讯作者：
Kozai, K
影响因子：
3
作者：
DASANAYAKE, AP;CAUFIELD, PW;KOHLER, B
通讯作者：
KOHLER, B
影响因子：
2.3
作者：
Berkowitz, R
通讯作者：
Berkowitz, R
影响因子：
--
作者：
KOHLER B;ANDREEN I;JONSSON B
通讯作者：
JONSSON B
影响因子：
4.2
作者：
Lindquist, B;Emilson, CG
通讯作者：
Emilson, CG