Human T-lymphotropic retroviruses
Human T-lymphotropic retroviruses
复制标题
人类嗜T淋巴细胞逆转录病毒
作者:
F. Wong;R. Gallo
The first human retroviruses have been discovered during the past six years. They cause two diseases which involve disturbances of the growth of the T4 lymphocyte, a remarkably specific target cell type. This cell, which is central to the regulation of the immune system, is induced by human T-lymphotropic virus type I (HTLV-I) to excessive proliferation (leukaemia) and by HTLV-III to premature death (acquired immune deficiency syndrome, AIDS). Both also seem to be indirectly involved in several other disorders. The genetic structures of these retroviruses and the mechanisms by which they usurp host-cell functions are novel among retroviruses.
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DOI:
10.1126/science.6603659
发表时间:
1983
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Essex,M;McLane,MF;Lee,TH;Tachibana,N;Mullins,JI;Kreiss,J;Kasper,CK;Poon,MC;Landay,A;Stein,SF;Francis,DP;Cabradilla,C;Lawrence,DN;Evatt,BL
通讯作者:
Evatt,BL
影响因子:
56.9
作者:
GONDA, MA;WONGSTAAL, F;GILDEN, RV
通讯作者:
GILDEN, RV
DOI:
10.1126/science.6093247
发表时间:
1984
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Groopman,JE;Salahuddin,SZ;Sarngadharan,MG;Markham,PD;Gonda,M;Sliski,A;Gallo,RC
通讯作者:
Gallo,RC
影响因子:
56.9
作者:
SODROSKI, J;ROSEN, C;HASELTINE, WA
通讯作者:
HASELTINE, WA
DOI:
10.1126/science.6091270
发表时间:
1984
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Wachsman,W;Shimotohno,K;Clark,SC;Golde,DW;Chen,IS
通讯作者:
Chen,IS