Biological basis of exercise-based treatments: spinal cord injury.
Biological basis of exercise-based treatments: spinal cord injury.
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DOI：
10.1016/j.pmrj.2011.02.019
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发表时间：
2011-06
期刊：
影响因子：
2.1
通讯作者：
Hansen, Christopher N.
中科院分区：
文献类型：
--
作者：
Basso, D. Michele;Hansen, Christopher N.
Despite intensive neurorehabilitation, extensive functional recovery after spinal cord injury is unattainable for most individuals. Optimal recovery will likely depend on activity-based, task-specific training that personalizes the timing of intervention with the severity of injury. Exercise paradigms elicit both beneficial and deleterious biophysical effects after spinal cord injury. Modulating the type, intensity, complexity, and timing of training may minimize risk and induce greater recovery. This review discusses the following: (a) the biological underpinning of training paradigms that promote motor relearning and recovery, and (b) how exercise interacts with cellular cascades after spinal cord injury. Clinical implications are discussed throughout.
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