Generational difference of refractive error in the baseline study of the Beijing Myopia Progression Study.
Generational difference of refractive error in the baseline study of the Beijing Myopia Progression Study.
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DOI：
10.1136/bjophthalmol-2012-302468
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发表时间：
2013-06
期刊：
影响因子：
--
通讯作者：
Ciuffreda KJ
中科院分区：
文献类型：
--
作者：
Liang YB;Lin Z;Vasudevan B;Jhanji V;Young A;Gao TY;Rong SS;Wang NL;Ciuffreda KJ
报告中国市区父母与子女的屈光不正差(RED)和估计的单代近视移位。研究对象为北京市近视进展研究入选的6~17岁 儿童及其父母。分别对儿童和父母进行睫状肌麻痹和非睫状肌麻痹屈光检查。RED定义为父母的平均球面当量(SE)与其子女的平均球面当量(SE)之间的差值。红色的二项式拟合曲线被绘制为儿童年龄的函数。代际近视漂移定义为18 岁时根据预测模型估计的RED。395个家庭参加了调查。红色与儿童年龄呈正相关(rspearman=0.58p<；0.001)。红光(中位数第25和第75个百分位数)为−1.88(−3.23~−1.00)屈光度(D)，16.0~17.9 岁儿童为1.53(−0.12~3.44)D。儿童的自尊在11 岁时接近父母的平均自尊。在18 岁时，儿童的近视偏移估计为1.94D。在这个样本中，11 岁儿童的屈光不正已经与他们的父母相似。此外，18岁 儿童的近视估计将比他们的父母高2.0D。这一显着的单代近视转变表明，环境因素可能对中国城市儿童的近视发展产生影响。
To report the refractive error difference (RED) between parents and their children and the estimated single generational myopic shift in an urban area in China. 395 children aged 6–17 years and their parents, who had been enrolled in the Beijing Myopia Progression Study were included. Cycloplegic and non-cycloplegic refraction of the children and parents were performed, respectively. RED was defined as the difference between the average parental spherical equivalent (SE) and the average SE of their children. Binomial fitted curves of RED were plotted as a function of the children's age. Generational myopic shift was defined as the estimated RED according to the prediction model at the age of 18 years. 395 families were enrolled. The RED was positively correlated with the children's age (rspearman=0.58, p<0.001). The RED (median (25th and 75th percentile)) was −1.88 (−3.23 to −1.00) dioptres (D) in children at 6.0–7.9 years of age, and it increased to 1.53 (−0.12 to 3.44) D in children at 16.0–17.9 years of age. The SE of the children approached the average SE of their parents at the age of 11 years. At the age of 18 years, the children's estimated myopic shift would be 1.94 D. In this sample, children's refractive errors at the age of 11 years were already similar to their parents. Moreover, the estimated myopia in children at the age of 18 years would be up to 2.0 D higher than their parents. This remarkable single-generation myopic shift indicates that there are likely effects of environmental factors on myopia development in urban Chinese children.
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影响因子：
1.4
作者：
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