Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents.
Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescents.
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DOI：
10.1016/j.jpeds.2009.01.015
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发表时间：
2009-06
影响因子：
5.1
通讯作者：
Hsu, Chi-Yuan
中科院分区：
文献类型：
--
作者：
Nguyen, Stephanie;Choi, Hyon K.;Lustig, Robert H.;Hsu, Chi-Yuan
为了评估含糖饮料的摄入量是否与青少年的血尿酸水平和血压升高有关，含糖饮料是饮食中果糖的重要来源。我们分析了1999-2004年全国健康与营养检查调查中4867名12-18岁青少年的横断面数据。饮食数据是通过24小时饮食回忆访谈进行评估的。含糖饮料包括水果饮料、运动饮料、汽水和加糖咖啡或茶。我们使用多元线性回归来评估含糖饮料的摄入量与血尿酸和血压之间的关系。喝更多含糖饮料的青少年往往是年龄较大的男性。在调整后的模型中，从含糖饮料消费的最低类别到最高类别，血尿酸增加了0.18 mg/dL，收缩压z分数增加了0.17(趋势分别为0.01和0.03)。这些来自具有全国代表性的美国青少年样本的结果表明，饮用更高的含糖饮料与更高的血尿酸水平和收缩压相关，这可能会导致下游的不良健康后果。
To evaluate whether sugar sweetened beverage consumption, a significant source of dietary fructose, is associated with higher serum uric acid levels and blood pressure in adolescents. We analyzed cross-sectional data from 4867 adolescents aged 12–18 years old in the National Health and Nutrition Examination Survey 1999–2004. Dietary data was assessed from 24-hour dietary recall interviews. Sugar sweetened beverages included fruit drinks, sports drinks, soda, and sweetened coffee or tea. We used multivariate linear regression to evaluate the association of sugar sweetened beverage consumption with serum uric acid and with blood pressure. Adolescents who drank more sugar sweetened beverages tended to be older and male. In the adjusted model, serum uric acid increased by 0.18 mg/dL and systolic blood pressure z-score increased by 0.17 from the lowest to the highest category of sugar sweetened beverage consumption (P for trend 0.01 and 0.03, respectively). These results from a nationally representative sample of US adolescents indicate that higher sugar sweetened beverage consumption is associated with higher serum uric acid levels and systolic blood pressure, which may lead to downstream adverse health outcomes.
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