Cardiovascular disease risk factors in a population‐based sample of Norwegian children and adolescents

Cardiovascular disease risk factors in a population‐based sample of Norwegian children and adolescents
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挪威儿童和青少年人群样本中的心血管疾病危险因素

DOI:
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发表时间:
2009
影响因子:
2.1
通讯作者:
L. Andersen
L. Andersen
中科院分区:
医学4区
文献类型:
--
作者:
J. Steene;E. Kolle;S. Anderssen;L. Andersen

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客观的。该研究的目的是描述挪威儿童和青少年心血管疾病(CVD)危险因素的分布,并评估心血管疾病危险因素的聚集程度。材料和方法。对来自全国各地的 9 岁和 15 岁儿童进行了随机抽样。在受邀参加的 2,818 名受试者中,有 2,299 名受试者接受,总体参与率为 82 %。结果。 9岁和15岁女孩和男孩主要危险因素的平均值(SD)值为:总胆固醇(TC)(mmol/L)分别为4.49(0.73)、4.37(0.68)、4.19(0.76)和3.80(0.69);甘油三酯(TG)(mmol/L)分别为0.72(0.33)、0.63(0.32)、0.79(0.32)和0.82(0.47);高密度脂蛋白胆固醇(HDL-c)(mmol/L)分别为1.70(0.35)、1.79(0.40)、1.61(0.34)和1.42(0.30);收缩压(mmHg)分别为102.6(7.7)、103.3(7.7)、109.0(8.8)和115.3(9.0);稳态模型评估评分(HOMA)分别为1.29(0.83)、1.19(0.78)、2.10(1.37)和2.14(1.49)。至少发现了 5 个风险因素,参与者数量是预期的 11.1 倍(95 % 置信区间 (CI) 8.76 至 13.44)。在 11.4 %(95 % CI,9.8 至 13.0)的研究人群中发现了 CVD 危险因素的显着聚集程度,9 岁和 15 岁儿童的平均 Z 得分分别为 1.24 (0.06) 和 1.04 (0.08)。结论。本研究提供了有关儿童和青少年选定的 CVD 危险因素的国家参考数据。
Objective. The objective of the study was to describe the distribution of cardiovascular disease (CVD) risk factors, and to evaluate the extent of clustering of CVD risk factors in Norwegian children and adolescents. Material and methods. A randomly selected cohort of 9‐year‐olds and 15‐year‐olds from all regions of the country was sampled. Of 2,818 subjects invited to participate, 2,299 accepted, giving an overall participation rate of 82 %. Results. Mean (SD) values for the main risk factors for 9‐year‐old and 15‐year‐old girls and boys were: total cholesterol (TC) (mmol/L) 4.49 (0.73), 4.37 (0.68), 4.19 (0.76) and 3.80 (0.69), respectively; triglycerides (TG) (mmol/L) 0.72 (0.33), 0.63 (0.32), 0.79 (0.32) and 0.82 (0.47), respectively; high density lipoprotein cholesterol (HDL‐c) (mmol/L) 1.70 (0.35), 1.79 (0.40), 1.61 (0.34) and 1.42 (0.30), respectively; systolic blood pressure (mmHg) 102.6 (7.7), 103.3 (7.7), 109.0 (8.8) and 115.3 (9.0), respectively; and homeostasis model assessment score (HOMA) 1.29 (0.83), 1.19 (0.78), 2.10 (1.37) and 2.14 (1.49), respectively. At least five risk factors were found in 11.1 (95 % confidence interval (CI) 8.76 to 13.44) times as many participants as expected. A significant degree of clustering of CVD risk factors was found in 11.4 % (95 % CI, 9.8 to 13.0) of the study population, and these had mean Z scores of 1.24 (0.06) and 1.04 (0.08) for the 9‐year‐olds and 15‐year‐olds, respectively. Conclusion. This study presents national reference data on selected CVD risk factors in children and adolescents.
青春期胆固醇、高密度脂蛋白胆固醇和甘油三酯:奥斯陆青年研究。
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