Gender and comorbidity among individuals with opioid use disorders in the NESARC study.

Gender and comorbidity among individuals with opioid use disorders in the NESARC study.
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DOI:
10.1016/j.addbeh.2009.01.002
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发表时间:
2009-06
影响因子:
4.4
通讯作者:
Moore, Alison A.
Moore, Alison A.
中科院分区:
医学2区
文献类型:
--
作者:
Grella, Christine E.;Karno, Mitchell P.;Warda, Umme S.;Niv, Noosha;Moore, Alison A.

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本研究探讨了美国阿片类药物使用障碍患者终身精神和物质使用障碍相关性的性别差异。样本(N=578)来自全国酒精及相关疾病流行病学调查(NESARC),这是一项具有代表性的家庭调查。进行双变量分析和logistic回归建模。大约70%的样本有一个终身非物质使用轴I障碍;女性约两倍的可能性,无论是情绪或焦虑症的男性。大约一半的样本有人格障碍,女性更容易患有偏执型人格障碍,男性更容易患有反社会人格障碍。患有终身精神障碍的人依赖其他物质的可能性是其他人的三倍,与性别无关。该研究表明,终身精神障碍和其他物质使用障碍之间存在反比关系,女性患几种精神障碍的几率明显较高,男性患其他物质使用障碍的几率较高。
This study examines gender differences in the association of lifetime mental and substance use disorders among individuals with opioid use disorders in the United States. The sample (N=578) is from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), which is a representative household survey. Bivariate analyses and logistic regression modeling were conducted. About 70% of the sample had a lifetime non-substance use Axis I disorder; women were about twice as likely as men to have either a mood or anxiety disorder. About half of the sample had a personality disorder, with women more likely to have paranoid disorder and men more likely to have antisocial personality disorder. Individuals with a lifetime mental disorder were about three times more likely than others to be dependent on other substances, independent of gender. The study demonstrated an inverse relationship between lifetime mental and other substance use disorders, with women having significantly higher odds for several of the mental disorders and men having greater odds of other substance use disorders.
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