"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.

"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.
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DOI:
10.1039/c0nr00192a
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发表时间:
2010-06
期刊:
影响因子:
6.7
通讯作者:
Xia Y
Xia Y
中科院分区:
材料科学2区
文献类型:
--
作者:
Xie J;Li X;Lipner J;Manning CN;Schwartz AG;Thomopoulos S;Xia Y

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我们已经证明了制造的“对齐随机”静电纺丝支架,模仿胶原纤维的结构组织在肌腱骨插入网站。肌腱成纤维细胞培养在这样的支架上表现出高度组织化和haphazardous定向形态,分别在对齐和随机部分。
We have demonstrated the fabrication of “aligned-to-random” electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions.
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