WormBase 2017: molting into a new stage.

WormBase 2017: molting into a new stage.
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DOI:
10.1093/nar/gkx998
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发表时间:
2018-01-04
影响因子:
14.9
通讯作者:
Sternberg PW
Sternberg PW
中科院分区:
生物学2区
文献类型:
--
作者:
Lee RYN;Howe KL;Harris TW;Arnaboldi V;Cain S;Chan J;Chen WJ;Davis P;Gao S;Grove C;Kishore R;Muller HM;Nakamura C;Nuin P;Paulini M;Raciti D;Rodgers F;Russell M;Schindelman G;Tuli MA;Van Auken K;Wang Q;Williams G;Wright A;Yook K;Berriman M;Kersey P;Schedl T;Stein L;Sternberg PW

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WormBase (http://www.wormbase.org) 是全球生物医学研究人员的重要知识资源。为了适应不断增加的研究数据数量和复杂性,WormBase 继续推进其数据采集、管理和检索实践,以最有效地提供有关秀丽隐杆线虫的全面知识以及有关其他线虫和寄生扁虫的基因组信息。最近显着的增强包括用户主导的数据提交,例如微型出版物;基因组数据管理和呈现,分别包括额外的基因组和 JBrowse;新的查询工具,例如SimpleMine、基因富集分析;新数据显示,例如人物谱系浏览器和基于本体的注释摘要。预计未来数据会更加快速增长,WormBase 继续迁移到尖端数据库技术,以实现更好的稳定性、可扩展性、可重复性和更快的响应时间。为了更好地服务于更广泛的研究界,WormBase 与其他五个模式生物数据库和基因本体项目开始正式合作,成立基因组资源联盟。
WormBase (http://www.wormbase.org) is an important knowledge resource for biomedical researchers worldwide. To accommodate the ever increasing amount and complexity of research data, WormBase continues to advance its practices on data acquisition, curation and retrieval to most effectively deliver comprehensive knowledge about Caenorhabditis elegans, and genomic information about other nematodes and parasitic flatworms. Recent notable enhancements include user-directed submission of data, such as micropublication; genomic data curation and presentation, including additional genomes and JBrowse, respectively; new query tools, such as SimpleMine, Gene Enrichment Analysis; new data displays, such as the Person Lineage browser and the Summary of Ontology-based Annotations. Anticipating more rapid data growth ahead, WormBase continues the process of migrating to a cutting-edge database technology to achieve better stability, scalability, reproducibility and a faster response time. To better serve the broader research community, WormBase, with five other Model Organism Databases and The Gene Ontology project, have begun to collaborate formally as the Alliance of Genome Resources.
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