Poor body condition is associated with lower hippocampal plasticity and higher gut methanogen abundance in adult laying hens from two housing systems.
Poor body condition is associated with lower hippocampal plasticity and higher gut methanogen abundance in adult laying hens from two housing systems.
复制标题
DOI：
10.1038/s41598-022-18504-1
复制
发表时间：
2022-09-15
影响因子：
4.6
通讯作者：
Smulders, T., V
中科院分区：
文献类型：
--
作者：
Armstrong, E. A.;Richards-Rios, P.;Addison, L.;Sandilands, V;Guy, J. H.;Wigley, P.;Boswell, T.;Smulders, T., V
目前还不清楚哪种商品房体系能为蛋鸡提供最好的生活质量。此外，系统内的压力水平存在很大的个体差异。海马神经发生或可塑性可以提供个体所经历的应激源的综合生物标志物。我们选择了12个成年母鸡，每个良好和不良的身体状况（基于身体大小，羽毛覆盖程度和红色的梳子）从一个多层自由放养系统包含H&N株母鸡，并从一个丰富的笼系统包含海兰母鸡（n = 48）。在海马中定量表达双皮质素（DCX）的未成熟神经元，对盲肠微生物组的内容物进行测序，并在脾脏中测量炎性细胞因子的表达。DCX+细胞密度在饲养系统之间没有差异。在这两个系统中，条件差的母鸡有较低的DCX+细胞密度，表现出脾白细胞介素-6（IL-6）mRNA的表达升高，并有较高的相对盲肠丰度的产甲烷古菌嗜甲烷菌科。研究结果表明，身体状况不佳是一个指标，个别母鸡经历了相对较大程度的累积慢性压力，并与身体状况不佳的母鸡的比例的调查可能是一种方法来评估住房制度对母鸡福利的影响。
It is still unclear which commercial housing system provides the best quality of life for laying hens. In addition, there are large individual differences in stress levels within a system. Hippocampal neurogenesis or plasticity may provide an integrated biomarker of the stressors experienced by an individual. We selected 12 adult hens each with good and poor body condition (based on body size, degree of feather cover and redness of the comb) from a multi-tier free range system containing H&N strain hens, and from an enriched cage system containing Hy-Line hens (n = 48 total). Immature neurons expressing doublecortin (DCX) were quantified in the hippocampus, contents of the caecal microbiome were sequenced, and expression of inflammatory cytokines was measured in the spleen. DCX+ cell densities did not differ between the housing systems. In both systems, poor condition hens had lower DCX+ cell densities, exhibited elevated splenic expression of interleukin-6 (IL6) mRNA, and had a higher relative caecal abundance of methanogenic archea Methanomethylophilaceae. The findings suggest poor body condition is an indicator that individual hens have experienced a comparatively greater degree of cumulative chronic stress, and that a survey of the proportion of hens with poor body conditions might be one way to evaluate the impact of housing systems on hen welfare.
登录
查看更多内容
DOI：
10.3390/ani4020374
发表时间：
2014-06-20
期刊：
Animals : an open access journal from MDPI
影响因子：
--
作者：
Bestman M;Wagenaar JP
通讯作者：
Wagenaar JP
影响因子：
2.5
作者：
Balthazart, Jacques;Ball, Gregory F.
通讯作者：
Ball, Gregory F.
影响因子：
2.3
作者：
BRADSHAW, RH
通讯作者：
BRADSHAW, RH
影响因子：
3.4
作者：
Couillard-Despres, S;Winner, B;Aigner, L
通讯作者：
Aigner, L
影响因子：
4.4
作者：
Birkl P;Bharwani A;Kjaer JB;Kunze W;McBride P;Forsythe P;Harlander-Matauschek A
通讯作者：
Harlander-Matauschek A