Rabbit heart fatty acid-binding protein. Isolation, characterization, and application of a monoclonal antibody.
Rabbit heart fatty acid-binding protein. Isolation, characterization, and application of a monoclonal antibody.
复制标题
兔心脏脂肪酸结合蛋白。
DOI：
10.1161/01.res.65.4.981
复制
发表时间：
1989
影响因子：
20.1
通讯作者：
Brecher,P
中科院分区：
文献类型：
--
作者：
Knowlton,AA;Burrier,RE;Brecher,P
A fatty acid-binding protein (FABP) was purified from rabbit heart and characterized with respect to size, isoelectric point, and tissue distribution. This protein was found in red muscle, diaphragm, and aorta, as well as in the heart. Amino acid composition of rabbit heart FABP differed only slightly from the human and rat proteins. Rabbit heart FABP was shown to bind two molecules of fatty acid. A monoclonal antibody was developed and used to demonstrate the feasibility of a one-step purification with affinity chromatography. Cross-reactivity was found between the human protein and the rabbit antibody, and an immunoassay was developed to human heart FABP. Levels of human heart FABP in the plasma of patients with acute myocardial infarction were significantly elevated (83 +/- 9 micrograms/ml) compared with patients with pulmonary edema (52 +/- 7 micrograms/ml) and normal volunteers (28 +/- 5 micrograms/ml; p less than 0.05, mean +/- SEM).
登录
查看更多内容
禽成红细胞增多症病毒温度敏感突变体：erbB 产物的表面表达与转化相关
影响因子：
64.5
作者：
H. Beug;M. Hayman
通讯作者：
M. Hayman
转化需要细胞表面表达 v-fms 编码的糖蛋白
影响因子：
5.3
作者：
M. Roussel;C. W. Rettenmier;A. Look;C. Sherr
通讯作者：
C. Sherr
来自 3-甲基胆蒽诱导的 BALB/c 小鼠 Meth A 肉瘤的 DNA 高频共转移转化表型和肿瘤特异性移植抗原。
DOI：
10.1073/pnas.78.12.7555
发表时间：
1981
影响因子：
11.1
作者：
Hopkins,N;Besmer,P;DeLeo,AB;Law,LW
通讯作者：
Law,LW
影响因子：
4.4
作者：
L. W. Hostetler;H. Ananthaswamy;M. Kripke
通讯作者：
L. W. Hostetler;H. Ananthaswamy;M. Kripke
肿瘤启动子可增强癌基因诱导的 C3H 10T1/2 细胞转化。
DOI：
10.1126/science.6436974
发表时间：
1984
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Hsiao,WL;Gattoni-Celli,S;Weinstein,IB
通讯作者：
Weinstein,IB