Longitudinal stability and developmental properties of salivary cortisol levels and circadian rhythms from childhood to adolescence.
Longitudinal stability and developmental properties of salivary cortisol levels and circadian rhythms from childhood to adolescence.
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DOI：
10.1002/dev.20607
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发表时间：
2012-07
影响因子：
2.2
通讯作者：
Essex, Marilyn J.
中科院分区：
文献类型：
--
作者：
Shirtcliff, Elizabeth A.;Allison, Amber L.;Armstrong, Jeffrey M.;Slattery, Marcia J.;Kalin, Ned H.;Essex, Marilyn J.
本研究的目的是 (1) 确定皮质醇及其昼夜节律的稳定、类似性状的成分，以及 (2) 研究 HPA 轴成熟发育轨迹的个体差异。在社区儿童样本 (N=357) 中，从 9 岁（三年级）到 15 岁（九年级）的四次评估中纵向收集了多个唾液皮质醇样本。复杂的统计模型检查了皮质醇水平及其随时间的变化；主要考虑年龄、青春期和性别的影响。除了特定情况和稳定的短期或特定时期的皮质醇成分外，皮质醇水平和昼夜节律还存在稳定的、类似性状的成分，涵盖从童年到青春期的过渡。随着年龄的增长和身体的发育，年轻人的皮质醇水平更高，昼夜节律也更平坦。女孩的皮质醇更高，昼夜节律更强，对整个青春期的发育影响更大。区分皮质醇水平及其昼夜节律的稳定、类似性状的组成部分，为研究 HPA 功能个体差异的假定机制提供了经验基础。研究结果还提供了有关影响 HPA 轴发育的成熟过程的重要描述性信息。
This study aimed to (1) identify a stable, trait-like component to cortisol and its circadian rhythm, and (2) investigate individual differences in developmental trajectories of HPA-axis maturation. Multiple salivary cortisol samples were collected longitudinally across four assessments from age 9 (3rd grade) through age 15 (9th grade) in a community sample of children (N=357). Sophisticated statistical models examined cortisol levels and its rhythm over time; effects of age, puberty and gender were primarily considered. In addition to situation-specific and stable short-term or epoch-specific cortisol components, there is a stable, trait-like component of cortisol levels and circadian rhythm across multiple years covering the transition from childhood into adolescence. Youth had higher cortisol and flatter circadian rhythms as they got older and more physically developed. Girls had higher cortisol, stronger circadian rhythms, and greater developmental influences across adolescence. Distinguishing a stable, trait-like component of cortisol level and its circadian rhythm provides the empirical foundation for investigating putative mechanisms underlying individual differences in HPA functioning. The findings also provide important descriptive information about maturational processes influencing HPA-axis development.
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影响因子：
5.8
作者：
Knutsson, U;Dahlgren, J;AlbertssonWikland, K
通讯作者：
AlbertssonWikland, K
影响因子：
3.5
作者：
Hibel, Leah C.;Granger, Douglas A.;Blair, Clancy
通讯作者：
Blair, Clancy
影响因子：
3.7
作者：
Granger, Douglas A.;Hibel, Leah C.;Kapelewski, Christine H.
通讯作者：
Kapelewski, Christine H.
影响因子：
3.7
作者：
KIRSCHBAUM, C;STEYER, R;HELLHAMMER, DH
通讯作者：
HELLHAMMER, DH
DOI：
10.1073/pnas.0605053103
发表时间：
2006-11-07
影响因子：
11.1
作者：
Adam, Emma K.;Hawkley, Louise C.;Cacioppo, John T.
通讯作者：
Cacioppo, John T.