Early warning of cotton bollworm resistance associated with intensive planting of Bt cotton in China.
Early warning of cotton bollworm resistance associated with intensive planting of Bt cotton in China.
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DOI：
10.1371/journal.pone.0022874
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Wu Y
中科院分区：
文献类型：
--
作者：
Zhang H;Yin W;Zhao J;Jin L;Yang Y;Wu S;Tabashnik BE;Wu Y
产生苏云金芽孢杆菌(Bt)毒素的转基因作物可以杀死一些关键的害虫，但害虫的抗性进化会降低它们的效力。延缓害虫对Bt作物抗性的主要策略需要非Bt寄主植物的避难所，以促进敏感害虫的生存。为了延缓对产生Bt毒素Cry1Ac的转基因棉花的抗虫性，美国和澳大利亚的农民种植了非Bt棉花的避难所，而中国的农民则依赖于棉花以外的非Bt寄主植物的“天然”避难所。本文报道了2010年中国北部地区棉铃虫(Helicoverpa Armigera)田间对Cry1Ac抗性的调查数据。室内生物测定结果表明，抗虫棉密集种植地中国北部的13个田间种群对Cry1Ac的感受性显著低于中国西北部棉区的2个种群。中国北部和西北部对Bt毒素Cry2Ab的敏感性没有差异，说明对Cry1Ac的抗性不会引起对Cry2Ab的交叉抗性，这表明中国北部对Cry1Ac的抗性是Bt棉对Cry1Ac的一种特异适应。尽管在实验室的生物检测中检测到了抗药性，但中国没有报告转Bt基因棉花的防治失败。这一早期预警可能会促使采取积极的应对措施，包括改用转基因棉花，产生两种或两种以上与Cry1A毒素不同的毒素。
Transgenic crops producing Bacillus thuringiensis (Bt) toxins kill some key insect pests, but evolution of resistance by pests can reduce their efficacy. The predominant strategy for delaying pest resistance to Bt crops requires refuges of non-Bt host plants to promote survival of susceptible pests. To delay pest resistance to transgenic cotton producing Bt toxin Cry1Ac, farmers in the United States and Australia planted refuges of non-Bt cotton, while farmers in China have relied on “natural” refuges of non-Bt host plants other than cotton. Here we report data from a 2010 survey showing field-evolved resistance to Cry1Ac of the major target pest, cotton bollworm (Helicoverpa armigera), in northern China. Laboratory bioassay results show that susceptibility to Cry1Ac was significantly lower in 13 field populations from northern China, where Bt cotton has been planted intensively, than in two populations from sites in northwestern China where exposure to Bt cotton has been limited. Susceptibility to Bt toxin Cry2Ab did not differ between northern and northwestern China, demonstrating that resistance to Cry1Ac did not cause cross-resistance to Cry2Ab, and implying that resistance to Cry1Ac in northern China is a specific adaptation caused by exposure to this toxin in Bt cotton. Despite the resistance detected in laboratory bioassays, control failures of Bt cotton have not been reported in China. This early warning may spur proactive countermeasures, including a switch to transgenic cotton producing two or more toxins distinct from Cry1A toxins.
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影响因子：
2.2
作者：
Tabashnik, Bruce E.;Van Rensburg, J. B. J.;Carriere, Yves
通讯作者：
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影响因子：
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作者：
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影响因子：
2.2
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影响因子：
1.7
作者：
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通讯作者：
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影响因子：
4.1
作者：
Carrière Y;Crowder DW;Tabashnik BE
通讯作者：
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