Nanotechnological strategies for engineering complex tissues.
Nanotechnological strategies for engineering complex tissues.
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DOI:
10.1038/nnano.2010.246
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发表时间:
2011-01
影响因子:
38.3
通讯作者:
中科院分区:
文献类型:
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Tissue engineering aims at developing functional substitutes for damaged tissues and organs. Before transplantation, cells are generally seeded on biomaterial scaffolds that recapitulate the extracellular matrix and provide cells with information that is important for tissue development. Here we review the nanocomposite nature of the extracellular matrix, describe the design considerations for different tissues and discuss the impact of nanostructures on the properties of scaffolds and their uses in monitoring the behaviour of engineered tissues. We also examine the different nanodevices used to trigger certain processes for tissue development, and offer our view on the principal challenges and prospects of applying nanotechnology in tissue engineering.
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DOI:
10.1073/pnas.0812242106
发表时间:
2009-09-01
影响因子:
11.1
作者:
Dvir, Tal;Kedem, Alon;Cohen, Smadar
通讯作者:
Cohen, Smadar
影响因子:
2.9
作者:
Bhattacharyya, Subhabrata;Kumbar, Sangamesh G.;Laurencin, Cato T.
通讯作者:
Laurencin, Cato T.
影响因子:
--
作者:
Alsberg, Eben;Feinstein, Efraim;Ingber, Donald E.
通讯作者:
Ingber, Donald E.
影响因子:
10.8
作者:
Cohen-Karni T;Qing Q;Li Q;Fang Y;Lieber CM
通讯作者:
Lieber CM
影响因子:
13.3
作者:
Dong, Bin;Smith, Meghan E.;Wnek, Gary E.
通讯作者:
Wnek, Gary E.