Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae.

Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae.
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不同类型的重组事件由酿酒酵母的 RAD1 和 RAD52 基因控制。

DOI:
10.1093/genetics/120.2.367
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发表时间:
1988
期刊:
影响因子:
3.3
通讯作者:
Klein,HL
Klein,HL
中科院分区:
生物学2区
文献类型:
--
作者:
Klein,HL

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研究了位于酿酒酵母染色体III和XV上的异等位基因重复内的染色体内重组。等位基因的两种可能的取向都被用于每次重复。三个重组类,基因转换,弹出和三倍,回收。某些重组类型是从重复的特定等位基因方向中无法预测的。这些意外重组体的回收需要RAD 1基因。这些研究表明,RAD1在重复序列之间的重组中起作用,并且重组事件是与交叉相关的基因转换。这些事件似乎涉及异源双链体区域的非常局部化的转换,并且与RAD 52介导的基因转换事件不同。证据也表明,大多数直接重复序列之间的重组事件是染色体内,而不是姐妹染色单体之间。
Intrachromosomal recombination within heteroallelic duplications located on chromosomes III and XV of Saccharomyces cerevisiae has been examined. Both possible orientations of alleles have been used in each duplication. Three recombinant classes, gene conversions, pop-outs and triplications, were recovered. Some of the recombinant classes were not anticipated from the particular allele orientation of the duplication. Recovery of these unexpected recombinants requires the RAD1 gene. These studies show that RAD1 has a role in recombination between repeated sequences, and that the recombination event is a gene conversion associated with a crossover. These events appear to involve very localized conversion of a heteroduplex region and are distinct from RAD52 mediated gene conversion events. Evidence is also presented to suggest that most recombination events between direct repeats are intrachromatid, not between sister chromatids.
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DOI: 10.1017/s0016672300015263
发表时间: 1974
期刊: Genetics Research
影响因子: 1.5
作者:
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通讯作者: H. L. K. Whitehouse
酿酒酵母中的染色体内重组:反向重复中的相互交换和相关基因转换。
DOI: 10.1093/genetics/117.4.633
发表时间: 1987
期刊: Genetics
影响因子: 3.3
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由重复酵母基因之间的高频减数分裂重组产生的染色体易位。
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发表时间: 1986
期刊: Genetics
影响因子: 3.3
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酿酒酵母中不依赖于 Rad52 的有丝分裂基因转换经常导致染色体丢失。
DOI: --
发表时间: 1985
期刊: Genetics
影响因子: 3.3
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通讯作者: M. Hearn
DOI: 10.1093/genetics/103.2.161
发表时间: 1983
期刊: Genetics
影响因子: 3.3
作者:
H. Sang;H. Whitehouse
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