Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes.

Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes.
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由重复酵母基因之间的高频减数分裂重组产生的染色体易位。

DOI:
10.1093/genetics/114.3.731
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发表时间:
1986
期刊:
影响因子:
3.3
通讯作者:
Petes,TD
Petes,TD
中科院分区:
生物学2区
文献类型:
--
作者:
Jinks-Robertson,S;Petes,TD

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相似文献

我们研究了酵母酿酒酵母中非同源染色体上重复基因之间的减数分裂和有丝分裂重组。这些实验的结果可以概括为三点。首先,非同源染色体重复序列之间的基因转换事件在减数分裂中频繁发生。这种转换事件的频率仅比同源染色体上等位基因位置处的基因之间的类似转换频率低17倍。第二,减数分裂和有丝分裂的转换事件之间的非同源染色体上的重复基因与相互重组的等位基因序列之间的转换相同的程度。重复基因之间的相互交换导致染色体易位。最后,非同源染色体上重复基因之间的重组在减数分裂中比在有丝分裂中更频繁地发生。
We have examined meiotic and mitotic recombination between repeated genes on nonhomologous chromosomes in the yeastSaccharomyces cerevisiae. The results of these experiments can be summarized in three statements. First, gene conversion events between repeats on nonhomologous chromosomes occur frequently in meiosis. The frequency of such conversion events is only 17-fold less than the analogous frequency of conversion between genes at allelic positions on homologous chromosomes. Second, meiotic and mitotic conversion events between repeated genes on nonhomologous chromosomes are associated with reciprocal recombination to the same extent as conversion between allelic sequences. The reciprocal exchanges between the repeated genes result in chromosomal translocations. Finally, recombination between repeated genes on nonhomologous chromosomes occurs much more frequently in meiosis than in mitosis.
DOI: 10.1016/s0092-8674(80)80052-3
发表时间: 1980-01-01
期刊: CELL
影响因子: 64.5
作者:
PETES, TD
通讯作者: PETES, TD
DOI: 10.1073/pnas.82.10.3350
发表时间: 1985-01-01
影响因子: 11.1
作者:
JINKSROBERTSON, S;PETES, TD
通讯作者: PETES, TD
有丝分裂重组机制
DOI: --
发表时间: 1981
期刊:
影响因子: --
作者:
M. Esposito;J. Wagstaff
通讯作者: J. Wagstaff
DOI: 10.1038/292306a0
发表时间: 1981-01-01
期刊: NATURE
影响因子: 64.8
作者:
JACKSON, JA;FINK, GR
通讯作者: FINK, GR
酿酒酵母中重复遗传元件之间的减数分裂重组。
DOI: 10.1093/genetics/109.2.303
发表时间: 1985
期刊: Genetics
影响因子: 3.3
作者:
Jackson,JA;Fink,GR
通讯作者: Fink,GR