Sleep and biological parameters in professional burnout: A psychophysiological characterization.
Sleep and biological parameters in professional burnout: A psychophysiological characterization.
复制标题
DOI：
10.1371/journal.pone.0190607
复制
发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Chennaoui M
中科院分区：
文献类型：
--
作者：
Metlaine A;Sauvet F;Gomez-Merino D;Boucher T;Elbaz M;Delafosse JY;Leger D;Chennaoui M
职业倦怠综合征与失眠、代谢、炎症和免疫相关。我们调查的兴趣，探索生物参数和睡眠障碍与倦怠症状的白领工人。对54名职业倦怠患者和86名健康对照者的职业等级、睡眠、工作紧张（Karasek问卷）、社会支持、焦虑和抑郁（HAD量表）进行比较。评估空腹血糖浓度、糖化血红蛋白（HbA 1C）、总胆固醇、甘油三酯、C反应蛋白（CRP）、促甲状腺激素（TSH）、25-羟基维生素D（25[OH]D）和白色血细胞（WBC）计数。采用方差分析和多元逐步Logistic回归分析方法对职业倦怠的预测因素进行分析。除了报告更多的工作压力（特别是工作控制，p = 0.02），焦虑水平较高（p<0.001），与失眠有关的睡眠障碍（OR = 21.5，95%CI = 8.8-52.3），职业倦怠的参与者表现出较高的HbA 1C、高血糖、CRP水平，较低的25（OH）D水平，较高的白细胞数量，嗜中性粒细胞和单核细胞（P均<0.001）和较高的总胆固醇（P = 0.01）。尤其是当HbA 1c> 3.5%时，倦怠的患病率从16.6%增加到60.0%（OR = 4.3，95%CI = 2.8-6.9）。HbA 1C与倦怠的两个维度（情绪耗竭和去人格化（r = 0.79和r = 0.71，p<0.01））呈显著正相关。模型包括工作紧张，工作满意度，焦虑和失眠没有预测倦怠（p = 0.30和p = 0.50）。然而，当包括HbA 1C水平时，倦怠的预测变得显著（P = 0.03）。我们的研究结果表明，睡眠和生物参数，特别是HbA 1C水平，在职业倦怠的表征的兴趣。
Professional burnout syndrome has been described in association with insomnia and metabolic, inflammatory and immune correlates. We investigated the interest of exploring biological parameters and sleep disturbances in relation to burnout symptoms among white-collar workers. Fifty-four participants with burnout were compared to 86 healthy control participants in terms of professional rank level, sleep, job strain (Karasek questionnaire), social support, anxiety and depression (HAD scale). Fasting concentrations of glycaemia, glycosylated hemoglobin (HbA1C), total-cholesterol, triglycerides, C-reactive protein (CRP), thyroid stimulating hormone (TSH), 25-hydroxyvitamin D (25[OH]D), and white blood cell (WBC) counts were assessed. Analysis of variance and a forward Stepwise Multiple Logistic Regression were made to identify predictive factors of burnout. Besides reporting more job strain (in particular job control p = 0.02), higher levels of anxiety (p<0.001), and sleep disorders related to insomnia (OR = 21.5, 95%CI = 8.8–52.3), participants with burnout presented higher levels of HbA1C, glycaemia, CRP, lower levels of 25(OH)D, higher number of leukocytes, neutrophils and monocytes (P<0.001 for all) and higher total-cholesterol (P = 0.01). In particular, when HbA1c is > 3.5%, the prevalence of burnout increases from 16.6% to 60.0% (OR = 4.3, 95%CI = 2.8–6.9). Strong significant positive correlation existed between HbA1C and the two dimensions (emotional exhaustion and depersonalization (r = 0.79 and r = 0.71, p<0.01)) of burnout. Models including job strain, job satisfaction, anxiety and insomnia did not predict burnout (p = 0.30 and p = 0.50). However, when HbA1C levels is included, the prediction of burnout became significant (P = 0.03). Our findings demonstrated the interest of sleep and biological parameters, in particular HbA1C levels, in the characterization of professional burnout.
登录
查看更多内容
影响因子：
3.3
作者：
Huth, Cornelia;Thorand, Barbara;Ladwig, Karl-Heinz
通讯作者：
Ladwig, Karl-Heinz
影响因子：
4.9
作者：
Kawakami, N;Akachi, K;Araki, S
通讯作者：
Araki, S
影响因子：
3.7
作者：
Beydoun MA;Gamaldo AA;Canas JA;Beydoun HA;Shah MT;McNeely JM;Zonderman AB
通讯作者：
Zonderman AB
影响因子：
3.7
作者：
Kachi Y;Nakao M;Takeuchi T;Yano E
通讯作者：
Yano E
影响因子：
4.7
作者：
Gominak, S. C.;Stumpf, W. E.
通讯作者：
Stumpf, W. E.