Inflammatory mechanisms of idiopathic epiretinal membrane formation.
Inflammatory mechanisms of idiopathic epiretinal membrane formation.
复制标题
特发性前膜形成的炎症机制。
DOI:
10.1155/2013/192582
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发表时间:
2013
影响因子:
4.6
通讯作者:
Christoforidis JB
中科院分区:
文献类型:
--
作者:
Joshi M;Agrawal S;Christoforidis JB
The pathogenesis of idiopathic epiretinal membranes (iERMs), a common pathology found in retina clinics, still eludes researchers to date. Ultrastructural studies of iERMs in the past have failed to identify the cells of origin due to the striking morphologic changes of cells involved via transdifferentiation. Thus, immunohistochemical techniques that stain for the cytostructural components of cells have confirmed the importance of glial cells and hyalocytes in iERM formation. The cellular constituents of iERMs are thought to consist of glial cells, fibroblasts, hyalocytes, etc. that, in concert with cytokines and growth factors present in the vitreous, lead to iERM formation. Recently, research has focused on the role of the posterior hyaloid in iERM formation and contraction, particularly the process of anomalous PVD as it relates to iERM formation. Recent advances in proteomics techniques have also elucidated the growth factors and cytokines involved in iERM formation, most notably nerve growth factor, glial cell line-derived growth factor, and transforming growth factor β1.
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影响因子:
4.4
作者:
Iannetti, Ludovico;Accorinti, Massimo;Pivetti-Pezzi, Paola
通讯作者:
Pivetti-Pezzi, Paola
DOI:
10.1097/iae.0b013e3182246e2a
发表时间:
2012-03-01
影响因子:
3.3
作者:
Gandorfer, Arnd;Haritoglou, Christos;Kampik, Anselm
通讯作者:
Kampik, Anselm
DOI:
10.1007/bf02384852
发表时间:
1974-01-01
期刊:
ALBRECHT VON GRAEFES ARCHIV FUR KLINISCHE UND EXPERIMENTELLE OPHTHALMOLOGIE
影响因子:
--
作者:
FOOS, RY
通讯作者:
FOOS, RY
影响因子:
4.1
作者:
Cassidy, L;Barry, P;Kennedy, S
通讯作者:
Kennedy, S
影响因子:
2.4
作者:
Llombart, Cristina;Nacher, Victor;Ruberte, Jesus
通讯作者:
Ruberte, Jesus