Gold nanorods based platforms for light-mediated theranostics.

Gold nanorods based platforms for light-mediated theranostics.
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基于金纳米棒的光介导治疗平台

DOI:
10.7150/thno.5409
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发表时间:
2013
期刊:
影响因子:
12.4
通讯作者:
Chen C
Chen C
中科院分区:
医学1区
文献类型:
--
作者:
Zhang Z;Wang J;Chen C

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由于金纳米棒具有可调谐的表面等离子体和光热效应,在成像、热疗和药物输送等生物医学领域具有广阔的应用前景。所有这些应用都可以通过近红外(NIR)光进行远程控制,这种光可以以最小的侧向侵袭深入人体组织。因此,AuNRs具有将影像诊断和治疗结合到一个单一系统中的潜力,并作为近红外光介导的治疗平台发挥作用。在此,我们综述了AuNRs在诊断和治疗应用方面的最新进展,重点介绍了联合应用于治疗的目的。
Due to their tunable surface plasmon and photothermal effects, gold nanorods (AuNRs) have proved to be promising in a wide range of biomedical applications such as imaging, hyperthermia therapy and drug delivery. All these applications can be remotely controlled by near infrared (NIR) light which can penetrate deep into human tissues with minimal lateral invasion. AuNRs thus hold the potential to combine both imaging diagnosis and therapeutic treatment into one single system and function as a NIR light-mediated theranostic platform. Herein we review recent progress in diagnostic and therapeutic applications of AuNRs with a highlight on combined applications for theranostic purposes.
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发表时间: 2012-03-12
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