Performances of a portable electrospinning apparatus.

Performances of a portable electrospinning apparatus.
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DOI:
10.1007/s10529-014-1760-6
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发表时间:
2015-05
影响因子:
2.7
通讯作者:
Ye, Hua
Ye, Hua
中科院分区:
工程技术4区
文献类型:
--
作者:
Mouthuy, Pierre-Alexis;Groszkowski, Lukasz;Ye, Hua

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为了证明便携式静电纺丝设备可以将各种聚合物纺丝成亚微米纤维,并提供可与台式机器生产的丝网质量相媲美的网目质量。我们设计了一种由电池供电的小型静电纺丝装置,它可以通过微控制器控制聚合物溶液的电压和流速。它可用于静电纺丝一系列常用的聚合物,包括聚(ε-己内酯)、聚(对二氧六环酮)、聚(乳酸-乙醇酸)、聚(3-羟基丁酸酯)、聚环氧乙烷、聚乙烯醇和聚乙烯醇缩丁醛。此外,电纺网的生产质量可与台式机器相媲美。我们还表明,便携式设备能够电喷珠粒和微粒。最后,我们通过演示静电纺丝在猪和人皮肤上的可能性,强调了该设备在伤口愈合应用方面的潜力。便携式电纺设备仍处于开发的早期阶段,但它们可能很快就会成为台式机器的一种有吸引力的替代品,特别是对于需要移动性和更高灵活性的用途,如伤口愈合应用。
To demonstrate that portable electrospinning devices can spin a wide range of polymers into submicron fibres and provide a mesh quality comparable to those produced with benchtop machines. We have designed a small, battery-operated electrospinning apparatus which enables control over the voltage and the flow rate of the polymer solution via a microcontroller. It can be used to electrospin a range of commonly used polymers including poly(ε-caprolactone), poly(p-dioxanone), poly(lactic-co-glycolic acid), poly(3-hydroxybutyrate), poly(ethylene oxide), poly(vinyl acohol) and poly(vinyl butyral). Moreover, electrospun meshes are produced with a quality comparable to a benchtop machine. We also show that the portable apparatus is able to electrospray beads and microparticles. Finally, we highlight the potential of the device for wound healing applications by demonstrating the possibility of electrospinning onto pig and human skins. Portable electrospinning devices are still at an early stage of development but they could soon become an attractive alternative to benchtop machines, in particular for uses that require mobility and a higher degree of flexibility, such as for wound healing applications.
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