A Platform for Cognitive Monitoring of Neurosurgical Patients During Hospitalization.
A Platform for Cognitive Monitoring of Neurosurgical Patients During Hospitalization.
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DOI：
10.3389/fnhum.2021.726998
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发表时间：
2021
影响因子：
2.9
通讯作者：
Watrous AJ
中科院分区：
文献类型：
--
作者：
Ashmaig O;Hamilton LS;Modur P;Buchanan RJ;Preston AR;Watrous AJ
癫痫患者的颅内记录越来越多地用于深入了解人类认知的电生理机制。目前对这些患者进行研究存在一些实际限制，包括患者和研究人员的可用性以及患者的认知能力，这限制了可以收集的任务相关数据的数量。先前的研究已经同步了临床音频、视频和神经记录以理解自然主义行为，但是这些记录以患者为中心以理解他们的癫痫发作符号学，因此没有捕获和同步患者经历的视听刺激。在这里，我们描述了一个在住院期间对神经外科患者进行认知监测的平台，该平台使患者和研究人员都受益。我们提供了该系统的完整规格，并描述了感知，记忆和睡眠研究中的一些示例用例。我们提供的结果，从病人被动地看电视作为证明的原则，自然主义的认知研究。我们的系统开辟了新的途径，收集更多的数据，每个病人使用现实世界的行为，提供了新的可能性，进行纵向研究的电生理基础的人类认知在自然条件下。
Intracranial recordings in epilepsy patients are increasingly utilized to gain insight into the electrophysiological mechanisms of human cognition. There are currently several practical limitations to conducting research with these patients, including patient and researcher availability and the cognitive abilities of patients, which limit the amount of task-related data that can be collected. Prior studies have synchronized clinical audio, video, and neural recordings to understand naturalistic behaviors, but these recordings are centered on the patient to understand their seizure semiology and thus do not capture and synchronize audiovisual stimuli experienced by patients. Here, we describe a platform for cognitive monitoring of neurosurgical patients during their hospitalization that benefits both patients and researchers. We provide the full specifications for this system and describe some example use cases in perception, memory, and sleep research. We provide results obtained from a patient passively watching TV as proof-of-principle for the naturalistic study of cognition. Our system opens up new avenues to collect more data per patient using real-world behaviors, affording new possibilities to conduct longitudinal studies of the electrophysiological basis of human cognition under naturalistic conditions.
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影响因子：
3.2
作者：
Jacobs J;Korolev IO;Caplan JB;Ekstrom AD;Litt B;Baltuch G;Fried I;Schulze-Bonhage A;Madsen JR;Kahana MJ
通讯作者：
Kahana MJ
影响因子：
5.3
作者：
Jiang, Xi;Gonzalez-Martinez, Jorge;Halgren, Eric
通讯作者：
Halgren, Eric
影响因子：
19.9
作者：
Jacobs, Joshua;Kahana, Michael J.
通讯作者：
Kahana, Michael J.
DOI：
10.1073/pnas.2021238118
发表时间：
2021-03-09
影响因子：
11.1
作者：
Pacheco Estefan D;Zucca R;Arsiwalla X;Principe A;Zhang H;Rocamora R;Axmacher N;Verschure PFMJ
通讯作者：
Verschure PFMJ
影响因子：
9.2
作者：
Hamilton, Liberty S.;Edwards, Erik;Chang, Edward F.
通讯作者：
Chang, Edward F.