Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.

Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.
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DOI:
10.1016/j.jaci.2010.10.007
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发表时间:
2010-12
期刊:
The Journal of allergy and clinical immunology
影响因子:
--
通讯作者:
Schwaninger JM
Schwaninger JM
中科院分区:
其他
文献类型:
--
作者:
NIAID-Sponsored Expert Panel;Boyce JA;Assa'ad A;Burks AW;Jones SM;Sampson HA;Wood RA;Plaut M;Cooper SF;Fenton MJ;Arshad SH;Bahna SL;Beck LA;Byrd-Bredbenner C;Camargo CA Jr;Eichenfield L;Furuta GT;Hanifin JM;Jones C;Kraft M;Levy BD;Lieberman P;Luccioli S;McCall KM;Schneider LC;Simon RA;Simons FE;Teach SJ;Yawn BP;Schwaninger JM

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食物过敏是一个重要的公共卫生问题,影响儿童和成人,并可能增加患病率。尽管有严重过敏反应甚至死亡的风险,但目前还没有治疗食物过敏的方法:这种疾病只能通过避免过敏原或治疗症状来控制。食物过敏的诊断和管理也可能因临床实践而异。最后,由于患者经常将非过敏性食物反应(如食物不耐受)与食物过敏混淆,因此公众中存在一种毫无根据的信念,即食物过敏的患病率高于实际情况。针对这些问题,国家过敏和传染病研究所与34个专业组织,联邦机构和患者倡导团体合作,领导了诊断和管理食物过敏的临床指南的制定。本指南旨在供各种医疗保健专业人员使用,包括家庭医生、临床专家和执业护士。该指南包括对食物过敏的共识定义,讨论通常与食物过敏相关的共病状况,并关注IgE介导和非IgE介导的食物反应。讨论的主题包括流行病学,自然史,诊断和食物过敏的管理,以及严重症状和过敏反应的管理。这些指南提供了43个简明的临床建议,并就目前患者管理中的争议点提供了额外的指导。它们还确定了当前科学知识中的差距,以便通过未来的研究加以解决。
Food allergy is an important public health problem that affects children and adults and may be increasing in prevalence. Despite the risk of severe allergic reactions and even death, there is no current treatment for food allergy: the disease can only be managed by allergen avoidance or treatment of symptoms. The diagnosis and management of food allergy also may vary from one clinical practice setting to another. Finally, because patients frequently confuse nonallergic food reactions, such as food intolerance, with food allergies, there is an unfounded belief among the public that food allergy prevalence is higher than it truly is. In response to these concerns, the National Institute of Allergy and Infectious Diseases, working with 34 professional organizations, federal agencies, and patient advocacy groups, led the development of clinical guidelines for the diagnosis and management of food allergy. These Guidelines are intended for use by a wide variety of health care professionals, including family practice physicians, clinical specialists, and nurse practitioners. The Guidelines include a consensus definition for food allergy, discuss comorbid conditions often associated with food allergy, and focus on both IgE-mediated and non-IgE-mediated reactions to food. Topics addressed include the epidemiology, natural history, diagnosis, and management of food allergy, as well as the management of severe symptoms and anaphylaxis. These Guidelines provide 43 concise clinical recommendations and additional guidance on points of current controversy in patient management. They also identify gaps in the current scientific knowledge to be addressed through future research.
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